Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   QWH96_RS10600 Genome accession   NZ_CP128987
Coordinates   2118421..2120403 (-) Length   660 a.a.
NCBI ID   WP_046177146.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NS3396     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2113421..2125403
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QWH96_RS10575 (QWH96_10575) - 2114263..2115533 (-) 1271 Protein_2041 competence/damage-inducible protein A -
  QWH96_RS10580 (QWH96_10580) - 2115657..2116010 (-) 354 WP_065957668.1 VOC family protein -
  QWH96_RS10585 (QWH96_10585) - 2116013..2116585 (-) 573 WP_003058799.1 DNA-3-methyladenine glycosylase I -
  QWH96_RS10590 (QWH96_10590) ruvA 2116595..2117188 (-) 594 WP_003058778.1 Holliday junction branch migration protein RuvA Machinery gene
  QWH96_RS10595 (QWH96_10595) - 2117190..2118410 (-) 1221 WP_003058727.1 MFS transporter -
  QWH96_RS10600 (QWH96_10600) hexB 2118421..2120403 (-) 1983 WP_046177146.1 DNA mismatch repair endonuclease MutL Machinery gene
  QWH96_RS10605 (QWH96_10605) hexA 2120530..2123085 (-) 2556 WP_015058136.1 DNA mismatch repair protein MutS Machinery gene
  QWH96_RS10610 (QWH96_10610) - 2123072..2123425 (-) 354 WP_003062220.1 YlbF family regulator -
  QWH96_RS10615 (QWH96_10615) argR 2123422..2123859 (-) 438 WP_003055516.1 arginine repressor -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74527.90 Da        Isoelectric Point: 5.4680

>NTDB_id=776892 QWH96_RS10600 WP_046177146.1 2118421..2120403(-) (hexB) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
MTKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQVTIDIEESGLKKIQITDNGEGMSPEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEDNHGSLLVAIGGEIETLEETSTPVGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVSFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTAKKMIAISNADLDFEVSGYVSLP
ELTRANRNYMTILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSKGLYYDPQRNDFFVKESDVSEKIPESNFHNTEIDKTVKDQR
TEQFPDLGENTGFSSVKRASRSQDEITDADHPGLDLKNKQKLSQMLTRLENEEQSVFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEE
EIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=776892 QWH96_RS10600 WP_046177146.1 2118421..2120403(-) (hexB) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
ATGACAAAAATTATTGAATTACCAGAAGTTCTCGCCAACCAAATTGCAGCTGGTGAAGTTGTAGAAAGGCCAGCGAGTGT
TGTCAAGGAATTGGTTGAGAATGCTATCGATGCTAAGAGTAGCCAAGTCACCATTGATATTGAAGAGTCTGGTCTCAAAA
AGATACAGATTACGGACAATGGTGAAGGGATGTCGCCTGAAGACCTTCCTTTGAGTTTGCGGCGACATGCTACCAGTAAA
ATAAAAAGTCAAAGTGATCTCTTTCGAATTAGAACACTTGGTTTTAGGGGAGAAGCCTTACCATCGGTTGCTTCTATCAG
TAAAATCACAATAAAAACAGCTACTAAGGAAGATAATCACGGTTCTCTTTTAGTTGCTATCGGCGGAGAGATTGAAACGC
TCGAGGAAACGTCGACGCCTGTAGGTACCAAGATTAAGGTTGAAAACCTTTTTTATAACACGCCTGCTCGCCTCAAATAC
ATGAAAAGTTTACAGGCAGAGTTAGCCCATATTGTTGATGTGGTCAATCGTTTGAGTTTGGCACATCCAGAAGTTTCTTT
CACCCTTATTAGTGATGGCCGTCAATTAACTCAGACATCCGGGACGGGGGACCTGCGGCAGGCTATTGCAGGGATTTATG
GCTTGAATACTGCCAAAAAAATGATTGCTATTTCCAATGCCGATTTGGACTTTGAAGTGTCGGGCTATGTCAGTTTACCA
GAGTTGACACGCGCCAACCGCAATTATATGACCATTTTAATCAATGGACGCTACATTAAAAATTTCTTGCTCAATCGGGC
TATTTTAGATGGTTACGGCTCTAAGTTGATGGTTGGACGTTTCCCAATTGTGGTGATTGATATTCAGATTGACCCCTATT
TGGCCGATGTCAATGTTCACCCTACTAAGCAAGAGGTCCGTATTTCAAAAGAGCGTGAGTTGATGGCTTTAATTAGTACG
GCGATTTCTGAAAGTCTTAAGGAGCAAGATTTGATTCCAGATGCTCTGGAGAACTTAGCTAAATCAAGCACACGACACTT
TTCTAAACCAGAGCAAACACAACTTCCATTACAATCTAAAGGGCTTTATTATGATCCTCAAAGAAATGACTTTTTTGTTA
AAGAATCGGATGTTTCTGAAAAAATACCTGAGAGTAATTTTCATAATACAGAGATTGACAAGACTGTAAAGGATCAAAGG
ACGGAGCAGTTTCCTGATTTAGGAGAGAATACAGGATTTTCCTCAGTAAAACGTGCTAGTCGATCACAGGATGAGATAAC
TGATGCTGATCACCCTGGACTTGATTTAAAAAACAAACAAAAGTTATCTCAAATGCTAACCCGTTTGGAAAATGAAGAGC
AATCAGTATTTCCCGAATTGGATTATTTTGGTCAGATGCACGGAACTTATCTCTTTGCTCAGGGAAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGGGTTAAATACGAATATTATCGTGATAAGATAGGTGAGGTTGACAGTAGTTT
ACAGCAGCTGTTGGTGCCCTATTTGTTTGAGTTTTCCGGCTCGGATTTCATTAACTTACAGGAGAAAATGGCACTCTTAA
ATGAAGTTGGTATCTTCCTAGAAGTTTATGGGCACAATACTTTCATTTTGAGAGAGCATCCTATCTGGATGAAAGAAGAA
GAGATTGCATCTGGTGTCTATGAAATGTGTGACATGTTACTTCTAACCAATGAGGTCTCTATCAAAACTTACCGAGCAGA
GTTAGCTATTATGATGAGTTGTAAACGATCTATCAAGGCAAATCATAGTTTGGATGATTATTCAGCAAGAAATCTGCTAC
TGCAATTAGCCCAATGTCAAAATCCTTATAACTGCCCTCATGGTAGACCCGTGTTGATTAATTTCAGTAAGGCAGATATG
GAAAAAATGTTCCGTCGTATCCAAGAAAATCATACTAGCCTGCGAGAGCTAGGAAAATATTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(462-604)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.012

100

0.689