Detailed information    

insolico Bioinformatically predicted

Overview


Name   recD   Type   Machinery gene
Locus tag   PH604_RS03965 Genome accession   NZ_CP116342
Coordinates   767285..769030 (+) Length   581 a.a.
NCBI ID   WP_047920976.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain SE690.     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 715414..776970 767285..769030 within 0
IS/Tn 769717..770718 767285..769030 flank 687


Gene organization within MGE regions


Location: 715414..776970
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PH604_RS03665 (PH604_03655) zwf 715459..716904 (+) 1446 WP_003688733.1 glucose-6-phosphate dehydrogenase -
  PH604_RS03670 (PH604_03660) pgl 717055..717750 (+) 696 WP_003688731.1 6-phosphogluconolactonase -
  PH604_RS03675 (PH604_03665) - 717731..718717 (+) 987 WP_003688729.1 glucokinase -
  PH604_RS03680 (PH604_03670) hexR 718766..719614 (+) 849 WP_003688727.1 DNA-binding transcriptional regulator HexR -
  PH604_RS03685 (PH604_03675) pgi 719840..721486 (+) 1647 WP_003688725.1 glucose-6-phosphate isomerase -
  PH604_RS11880 (PH604_03680) - 721703..722716 (+) 1014 WP_003688721.1 lysozyme inhibitor LprI family protein -
  PH604_RS03695 (PH604_03685) - 722761..722901 (+) 141 WP_003688719.1 hypothetical protein -
  PH604_RS03700 (PH604_03690) - 723083..723388 (+) 306 WP_225577434.1 type II toxin-antitoxin system HicB family antitoxin -
  PH604_RS11765 - 723472..723603 (-) 132 Protein_723 DNA helicase UvrD -
  PH604_RS11885 - 723600..723709 (-) 110 Protein_724 IS5/IS1182 family transposase -
  PH604_RS11770 - 723711..723872 (-) 162 Protein_725 DNA helicase UvrD -
  PH604_RS03715 (PH604_03705) - 723851..724464 (-) 614 Protein_726 hypothetical protein -
  PH604_RS11890 - 724549..724828 (+) 280 Protein_727 type II toxin-antitoxin system RelE/ParE family toxin -
  PH604_RS03730 (PH604_03720) - 724836..725147 (+) 312 WP_003704000.1 HigA family addiction module antitoxin -
  PH604_RS03735 (PH604_03725) - 725163..725492 (-) 330 WP_003691215.1 hypothetical protein -
  PH604_RS03740 (PH604_03730) - 725591..727842 (-) 2252 Protein_730 tail fiber protein -
  PH604_RS03745 (PH604_03735) - 727882..728445 (-) 564 WP_003695326.1 phage tail protein -
  PH604_RS03750 (PH604_03740) - 728621..729091 (-) 471 Protein_732 baseplate J/gp47 family protein -
  PH604_RS03755 (PH604_03745) - 729352..729678 (-) 327 WP_003688709.1 GPW/gp25 family protein -
  PH604_RS11895 (PH604_03750) - 729675..729869 (-) 195 WP_010358072.1 baseplate assembly protein -
  PH604_RS11900 (PH604_03755) - 729955..730254 (-) 300 Protein_735 phage baseplate assembly protein V -
  PH604_RS03770 (PH604_03760) - 730360..730572 (-) 213 WP_002243493.1 helix-turn-helix domain-containing protein -
  PH604_RS03775 (PH604_03765) - 730627..731280 (-) 654 WP_104691952.1 IS1595 family transposase -
  PH604_RS03780 (PH604_03770) - 731302..731586 (-) 285 WP_003706224.1 hypothetical protein -
  PH604_RS03785 (PH604_03775) - 731623..731886 (-) 264 WP_003688704.1 hypothetical protein -
  PH604_RS03790 (PH604_03780) - 731906..732154 (-) 249 WP_003695320.1 hypothetical protein -
  PH604_RS03795 (PH604_03785) - 732115..733185 (-) 1071 WP_003695318.1 tyrosine-type recombinase/integrase -
  PH604_RS03800 (PH604_03790) - 733394..734173 (-) 780 WP_003688701.1 ferredoxin--NADP reductase -
  PH604_RS03805 (PH604_11680) - 734765..734974 (-) 210 WP_003688699.1 hypothetical protein -
  PH604_RS03810 (PH604_03795) dinB 735073..736131 (+) 1059 WP_041421282.1 DNA polymerase IV -
  PH604_RS03815 (PH604_03800) rep 736201..738216 (-) 2016 WP_003704006.1 DNA helicase Rep -
  PH604_RS03820 (PH604_03805) aroD 738236..739000 (-) 765 WP_003688696.1 type I 3-dehydroquinate dehydratase -
  PH604_RS03825 (PH604_03810) recA 739200..740246 (+) 1047 WP_050164436.1 recombinase RecA Machinery gene
  PH604_RS03830 (PH604_03815) - 740899..741234 (-) 336 WP_003688693.1 YbaB/EbfC family nucleoid-associated protein -
  PH604_RS03835 (PH604_03820) dnaX 741315..743438 (-) 2124 WP_003691207.1 DNA polymerase III subunit gamma/tau -
  PH604_RS03840 (PH604_03825) mutL 743533..745497 (-) 1965 WP_003697109.1 DNA mismatch repair endonuclease MutL -
  PH604_RS03845 (PH604_03830) - 745641..745826 (+) 186 WP_003688687.1 DUF3460 family protein -
  PH604_RS03850 (PH604_03835) - 745837..746505 (+) 669 WP_003688686.1 class I SAM-dependent methyltransferase -
  PH604_RS03855 (PH604_03840) - 746505..747218 (+) 714 WP_003697104.1 tetratricopeptide repeat protein -
  PH604_RS03860 (PH604_03845) purE 747266..747751 (+) 486 WP_003688684.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  PH604_RS03865 (PH604_03850) - 747963..748828 (-) 866 Protein_755 transposase -
  PH604_RS03870 (PH604_03855) - 749145..749510 (+) 366 Protein_756 transposase -
  PH604_RS03875 (PH604_03860) - 749517..750542 (+) 1026 Protein_757 autotransporter outer membrane beta-barrel domain-containing protein -
  PH604_RS03880 (PH604_03865) - 750737..751393 (-) 657 WP_003688682.1 response regulator -
  PH604_RS03885 (PH604_03870) - 751390..753159 (-) 1770 WP_003695308.1 histidine kinase -
  PH604_RS03890 (PH604_03875) - 753366..753980 (+) 615 WP_003691204.1 molybdenum cofactor guanylyltransferase -
  PH604_RS03895 (PH604_03880) - 754143..754760 (+) 618 WP_010358100.1 riboflavin synthase -
  PH604_RS03900 (PH604_03885) - 754768..755631 (+) 864 WP_003693081.1 ATP-binding protein -
  PH604_RS03905 (PH604_03890) - 755644..756075 (-) 432 WP_272656725.1 Spy/CpxP family protein refolding chaperone -
  PH604_RS03910 (PH604_03895) rpe 756221..756904 (+) 684 WP_003688675.1 ribulose-phosphate 3-epimerase -
  PH604_RS03915 (PH604_03900) ruvB 757149..758180 (-) 1032 WP_003688673.1 Holliday junction branch migration DNA helicase RuvB -
  PH604_RS03920 (PH604_03905) - 758262..758570 (-) 309 WP_003688671.1 hypothetical protein -
  PH604_RS03925 (PH604_03910) - 758989..760221 (-) 1233 WP_003688669.1 multifunctional CCA addition/repair protein -
  PH604_RS03930 (PH604_03915) - 760300..761928 (-) 1629 WP_010951119.1 ABC-F family ATPase -
  PH604_RS03935 (PH604_03920) - 762078..762452 (+) 375 WP_003688664.1 arsenate reductase -
  PH604_RS03940 (PH604_03925) - 762501..764039 (+) 1539 WP_003695299.1 SurA N-terminal domain-containing protein -
  PH604_RS03945 (PH604_03930) recR 764106..764723 (+) 618 WP_003688660.1 recombination mediator RecR -
  PH604_RS03950 (PH604_03935) - 764779..765057 (-) 279 WP_003688659.1 hypothetical protein -
  PH604_RS03955 (PH604_03940) - 765283..766530 (+) 1248 WP_003691197.1 lipoprotein-releasing ABC transporter permease subunit -
  PH604_RS03960 (PH604_03945) lolD 766523..767218 (+) 696 WP_003688655.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  PH604_RS03965 (PH604_03950) recD 767285..769030 (+) 1746 WP_047920976.1 exodeoxyribonuclease V subunit alpha Machinery gene
  PH604_RS03970 (PH604_03955) - 769102..769748 (-) 647 Protein_776 methyltransferase -
  PH604_RS03975 (PH604_03960) - 769756..770718 (+) 963 WP_202838366.1 IS110 family transposase -
  PH604_RS03980 (PH604_03965) - 770847..771306 (-) 460 Protein_778 methyltransferase -
  PH604_RS03985 (PH604_03970) lon 771558..774020 (+) 2463 WP_003691187.1 endopeptidase La -
  PH604_RS03990 (PH604_03975) - 774202..774471 (+) 270 WP_003688640.1 HU family DNA-binding protein -
  PH604_RS03995 (PH604_03980) - 774647..775081 (-) 435 WP_003688638.1 hypothetical protein -
  PH604_RS04000 (PH604_03985) - 775074..776381 (-) 1308 WP_003688637.1 homoserine dehydrogenase -
  PH604_RS04005 (PH604_03990) - 776577..776948 (+) 372 WP_003688636.1 Mth938-like domain-containing protein -

Sequence


Protein


Download         Length: 581 a.a.        Molecular weight: 63113.87 Da        Isoelectric Point: 5.8825

>NTDB_id=776759 PH604_RS03965 WP_047920976.1 767285..769030(+) (recD) [Neisseria gonorrhoeae strain SE690.]
MELQTDEFAQAAARAAIRFLERYAGSGNEVLANCTERLFQALQNGHSFIRLSGDEADALSALAPVVGTSAAPLILEGRRL
FLGRMWQLEYDLAAEIKRLAAAGTSAPDAAGARQNLAKWFQGAGSEGQRDAAALALLQFFMVITGGPGTGKTTTVAKLLA
LICGENENLPHIALAAPTGKAAAHMARALHRSINGFDAPEAVRRHLLKLEGQTVHRLLKLSPPKMQAAFDHIRPLPFDVL
IVDEASMLDTALMLQLLKAVKTGARVILLGDENQLPSVGIGAVLSVLSQKTVLDGETHQRLAGFLPEHGFSVSANPPVLA
QNTAHLSFSHRFGDNSGIGCLARAAVSGDEGAWALFDRFPDELEHSECSPNARVERLYRAHKAYWQAVKDGNIEAAYAGI
SDIVVLAAWRQDAEDFNEAYCSYVRRKMNIPEHLAYFAGEPIMIRQNDYALELFNGDIGLIMEDVGRQGSLAAYFADADG
FKKVAVSCLPEFEPAFAMTVHKSQGSEYREVWLLPPSDAPSDEGDDALSGLSKELLYTAITRAREKFVFFGGKKTFCQAV
NTVKVRQTALDSMLERVFSQE

Nucleotide


Download         Length: 1746 bp        

>NTDB_id=776759 PH604_RS03965 WP_047920976.1 767285..769030(+) (recD) [Neisseria gonorrhoeae strain SE690.]
ATGGAACTGCAGACAGATGAATTTGCCCAAGCGGCGGCAAGGGCGGCAATCCGTTTTTTGGAACGCTATGCGGGTTCGGG
CAACGAAGTGCTTGCAAACTGTACCGAACGCCTGTTTCAGGCATTGCAAAACGGTCATTCGTTTATCCGTTTGAGCGGGG
ACGAGGCTGACGCGCTGTCGGCACTCGCACCCGTGGTCGGAACATCCGCCGCGCCTTTGATTTTGGAAGGCAGAAGGCTG
TTTTTGGGCAGGATGTGGCAGTTGGAATACGATTTGGCTGCCGAAATAAAACGCTTGGCGGCAGCCGGCACGTCCGCCCC
CGACGCGGCAGGCGCGCGGCAAAACCTCGCAAAATGGTTTCAAGGCGCGGGAAGCGAAGGACAGCGCGATGCGGCCGCCT
TGGCACTGTTGCAGTTTTTTATGGTGATTACCGGAGGGCCGGGAACGGGCAAAACGACAACGGTTGCCAAACTGCTGGCA
CTGATTTGCGGTGAAAACGAAAATCTTCCCCATATCGCGCTTGCCGCACCGACGGGCAAAGCGGCGGCACATATGGCGCG
CGCGCTGCACCGTTCAATCAACGGTTTTGACGCGCCGGAGGCCGTCCGCCGCCATTTGCTCAAACTGGAAGGGCAAACCG
TCCACCGACTGCTTAAGCTGAGCCCGCCCAAAATGCAGGCGGCGTTCGACCATATCCGTCCGCTGCCGTTCGACGTGCTG
ATTGTCGATGAAGCCTCCATGTTGGATACCGCATTGATGCTGCAACTTTTGAAAGCGGTCAAAACCGGCGCGCGCGTGAT
TCTGCTGGGCGATGAAAACCAGCTCCCGTCCGTCGGAATCGGGGCGGTGCTGTCCGTTTTGTCGCAAAAAACCGTTTTGG
ACGGAGAAACGCACCAAAGGCTGGCCGGTTTCCTTCCGGAACACGGTTTCAGCGTCAGCGCAAATCCGCCCGTGTTGGCG
CAAAACACCGCCCATCTGTCGTTCAGCCACCGCTTCGGCGACAACAGCGGCATCGGCTGCCTTGCCCGTGCCGCCGTATC
GGGCGATGAAGGGGCGTGGGCATTGTTTGACCGGTTTCCGGACGAACTGGAACATTCGGAATGCAGTCCGAATGCTCGGG
TCGAAAGGTTGTACCGGGCGCACAAAGCCTATTGGCAGGCGGTAAAAGACGGCAATATCGAAGCCGCATACGCAGGTATC
TCGGATATCGTGGTTCTGGCAGCTTGGCGGCAGGATGCGGAAGACTTCAACGAAGCCTATTGCAGCTATGTACGCCGCAA
AATGAACATACCGGAACATTTGGCCTATTTCGCCGGAGAGCCGATTATGATCAGACAGAACGACTACGCGCTTGAGCTGT
TCAACGGCGACATCGGACTGATTATGGAAGATGTCGGACGGCAGGGCAGCCTTGCCGCCTATTTTGCCGATGCGGACGGA
TTTAAAAAGGTAGCGGTAAGCTGCCTGCCCGAATTTGAACCCGCATTCGCCATGACCGTCCACAAAAGCCAAGGTTCGGA
ATATCGGGAAGTCTGGCTGCTGCCGCCTTCCGACGCACCTTCGGACGAAGGGGACGATGCATTGTCCGGATTGAGTAAGG
AGCTGTTATATACCGCCATTACCCGCGCCAGGGAAAAATTCGTATTTTTCGGCGGCAAAAAGACATTTTGTCAGGCGGTA
AACACCGTCAAAGTCCGTCAGACGGCGTTGGACAGTATGCTTGAGCGGGTATTTTCACAAGAATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recD Neisseria gonorrhoeae strain FA1090

99.828

100

0.998