Detailed information
Bioinformatically predicted
Overview
| Name | sxy/tfoX | Type | Regulator |
| Locus tag | PIC88_RS08640 | Genome accession | NZ_CP116188 |
| Coordinates | 1775868..1776497 (+) | Length | 209 a.a. |
| NCBI ID | WP_000839153.1 | Uniprot ID | A0A9Q6Y251 |
| Organism | Escherichia coli strain DETEC-E223 | ||
| Function | positive regulator of competence gene (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1748032..1785669 | 1775868..1776497 | within | 0 |
Gene organization within MGE regions
Location: 1748032..1785669
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PIC88_RS08510 (PIC88_08505) | ssuD | 1748237..1749382 (-) | 1146 | WP_000056006.1 | FMNH2-dependent alkanesulfonate monooxygenase | - |
| PIC88_RS08515 (PIC88_08510) | ssuA | 1749379..1750338 (-) | 960 | WP_001244308.1 | aliphatic sulfonate ABC transporter substrate-binding protein SsuA | - |
| PIC88_RS08520 (PIC88_08515) | ssuE | 1750331..1750906 (-) | 576 | WP_001263933.1 | NADPH-dependent FMN reductase | - |
| PIC88_RS08525 (PIC88_08520) | elfA | 1751262..1751801 (+) | 540 | WP_000750293.1 | fimbrial protein | - |
| PIC88_RS08530 (PIC88_08525) | elfD | 1751884..1752585 (+) | 702 | WP_001295349.1 | molecular chaperone | - |
| PIC88_RS08535 (PIC88_08530) | elfC | 1752610..1755210 (+) | 2601 | WP_000286312.1 | fimbrial biogenesis usher protein | - |
| PIC88_RS08540 (PIC88_08535) | - | 1755201..1755842 (+) | 642 | Protein_1672 | fimbrial protein | - |
| PIC88_RS08545 (PIC88_08540) | - | 1755933..1757161 (+) | 1229 | WP_088895425.1 | IS3-like element IS2 family transposase | - |
| PIC88_RS08550 (PIC88_08545) | - | 1757173..1757607 (+) | 435 | Protein_1674 | fimbrial protein | - |
| PIC88_RS08555 (PIC88_08550) | ycbU | 1757619..1758161 (+) | 543 | WP_000730614.1 | fimbrial protein | - |
| PIC88_RS08560 (PIC88_08555) | ycbV | 1758169..1758684 (+) | 516 | WP_000919497.1 | fimbrial protein | - |
| PIC88_RS08565 (PIC88_08560) | ycbF | 1758650..1759387 (+) | 738 | WP_001111465.1 | fimbrial chaperone | - |
| PIC88_RS08570 (PIC88_08565) | pyrD | 1759498..1760508 (+) | 1011 | WP_001295352.1 | quinone-dependent dihydroorotate dehydrogenase | - |
| PIC88_RS08575 (PIC88_08570) | zapC | 1760682..1761224 (+) | 543 | WP_001295353.1 | cell division protein ZapC | - |
| PIC88_RS08580 (PIC88_08575) | ycbX | 1761221..1762330 (-) | 1110 | WP_000212422.1 | 6-N-hydroxylaminopurine resistance protein YcbX | - |
| PIC88_RS08585 (PIC88_08580) | rlmKL | 1762574..1764682 (+) | 2109 | WP_001086538.1 | bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL | - |
| PIC88_RS08590 (PIC88_08585) | uup | 1764694..1766601 (+) | 1908 | WP_000053099.1 | ABC transporter ATP-binding protein | - |
| PIC88_RS08595 (PIC88_08590) | pqiA | 1766731..1767984 (+) | 1254 | WP_000333176.1 | membrane integrity-associated transporter subunit PqiA | - |
| PIC88_RS08600 (PIC88_08595) | pqiB | 1767989..1769629 (+) | 1641 | WP_000445533.1 | intermembrane transport protein PqiB | - |
| PIC88_RS08605 (PIC88_08600) | pqiC | 1769626..1770189 (+) | 564 | WP_000759120.1 | membrane integrity-associated transporter subunit PqiC | - |
| PIC88_RS08610 (PIC88_08605) | rmf | 1770445..1770612 (+) | 168 | WP_000828648.1 | ribosome modulation factor | - |
| PIC88_RS08615 (PIC88_08610) | fabA | 1770682..1771200 (-) | 519 | WP_000227927.1 | bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase | - |
| PIC88_RS08620 (PIC88_08615) | ycbZ | 1771269..1773029 (-) | 1761 | WP_000152888.1 | AAA family ATPase | - |
| PIC88_RS08625 (PIC88_08620) | matP | 1773215..1773667 (+) | 453 | WP_000877161.1 | macrodomain Ter protein MatP | - |
| PIC88_RS08630 (PIC88_08625) | ompA | 1773743..1774783 (-) | 1041 | WP_000750416.1 | porin OmpA | - |
| PIC88_RS08635 (PIC88_08630) | sulA | 1775140..1775649 (-) | 510 | WP_000288710.1 | SOS-induced cell division inhibitor SulA | - |
| PIC88_RS08640 (PIC88_08635) | sxy/tfoX | 1775868..1776497 (+) | 630 | WP_000839153.1 | CRP-S regulon transcriptional coactivator Sxy | Regulator |
| PIC88_RS08645 (PIC88_08640) | yccS | 1776460..1778622 (-) | 2163 | WP_072310825.1 | YccS family putative transporter | - |
| PIC88_RS08650 (PIC88_08645) | yccF | 1778632..1779078 (-) | 447 | WP_001261235.1 | YccF domain-containing protein | - |
| PIC88_RS08655 (PIC88_08650) | helD | 1779201..1781255 (+) | 2055 | WP_001295354.1 | DNA helicase IV | - |
| PIC88_RS08660 (PIC88_08655) | mgsA | 1781287..1781745 (-) | 459 | WP_000424181.1 | methylglyoxal synthase | - |
| PIC88_RS08665 (PIC88_08660) | csgI | 1781841..1782503 (-) | 663 | WP_000847791.1 | DUF2057 family protein | - |
| PIC88_RS08670 (PIC88_08665) | yccU | 1782676..1783089 (+) | 414 | WP_001301418.1 | CoA-binding protein | - |
| PIC88_RS08675 (PIC88_08670) | hspQ | 1783134..1783451 (-) | 318 | WP_001295356.1 | heat shock protein HspQ | - |
| PIC88_RS08680 (PIC88_08675) | rlmI | 1783509..1784699 (-) | 1191 | WP_000116297.1 | 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI | - |
| PIC88_RS08685 (PIC88_08680) | yccX | 1784794..1785072 (+) | 279 | WP_000048252.1 | acylphosphatase | - |
| PIC88_RS08690 (PIC88_08685) | tusE | 1785069..1785398 (-) | 330 | WP_000904442.1 | sulfurtransferase TusE | - |
Sequence
Protein
Download Length: 209 a.a. Molecular weight: 24147.02 Da Isoelectric Point: 9.2180
>NTDB_id=776039 PIC88_RS08640 WP_000839153.1 1775868..1776497(+) (sxy/tfoX) [Escherichia coli strain DETEC-E223]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
Nucleotide
Download Length: 630 bp
>NTDB_id=776039 PIC88_RS08640 WP_000839153.1 1775868..1776497(+) (sxy/tfoX) [Escherichia coli strain DETEC-E223]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| sxy/tfoX | Escherichia coli BW25113 strain K-12 |
100 |
100 |
1 |