Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   PEZ79_RS10490 Genome accession   NZ_CP116023
Coordinates   2164104..2165912 (-) Length   602 a.a.
NCBI ID   WP_123831403.1    Uniprot ID   -
Organism   Enterococcus faecium strain CQFYH22-006     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2159104..2170912
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PEZ79_RS10465 (PEZ79_10465) - 2160144..2161043 (-) 900 WP_123827940.1 RluA family pseudouridine synthase -
  PEZ79_RS10470 (PEZ79_10470) - 2161045..2161842 (-) 798 WP_002289847.1 NAD kinase -
  PEZ79_RS10475 (PEZ79_10475) - 2161820..2162524 (-) 705 WP_002289848.1 GTP pyrophosphokinase family protein -
  PEZ79_RS10480 (PEZ79_10480) - 2162655..2163230 (+) 576 WP_002289849.1 CYTH domain-containing protein -
  PEZ79_RS10485 (PEZ79_10485) - 2163348..2164025 (+) 678 WP_002289850.1 ClpXP adapter SpxH family protein -
  PEZ79_RS10490 (PEZ79_10490) pepF 2164104..2165912 (-) 1809 WP_123831403.1 oligoendopeptidase F Regulator
  PEZ79_RS10495 (PEZ79_10495) - 2166088..2166482 (-) 395 Protein_2058 competence protein CoiA -
  PEZ79_RS10500 (PEZ79_10500) - 2166552..2167591 (+) 1040 WP_113843804.1 IS630 family transposase -
  PEZ79_RS10505 (PEZ79_10505) - 2167613..2168127 (-) 515 Protein_2060 competence protein CoiA family protein -
  PEZ79_RS10510 (PEZ79_10510) - 2168223..2169176 (+) 954 WP_002325884.1 IS30 family transposase -
  PEZ79_RS10515 (PEZ79_10515) - 2169189..2169290 (-) 102 Protein_2062 competence protein CoiA -
  PEZ79_RS10520 (PEZ79_10520) - 2169517..2170170 (-) 654 WP_271291965.1 adaptor protein MecA -
  PEZ79_RS10525 (PEZ79_10525) spxA 2170502..2170900 (-) 399 WP_002296384.1 transcriptional regulator SpxA -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 69702.05 Da        Isoelectric Point: 4.7020

>NTDB_id=775363 PEZ79_RS10490 WP_123831403.1 2164104..2165912(-) (pepF) [Enterococcus faecium strain CQFYH22-006]
MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEKLKQSEKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAH
LKNDQDTGNTDYQALYARASSLFSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAAFKGLYSVYEQFRNTFASTLGTH
IKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVDVVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTY
EEAKEKALEALKPMGEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHEMGHSVHSY
FTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHYLDGFKGTVFRQTQFAEFEHFMHTEDEKGVP
LTSEYLSDSYGKLNAKYYGPAVEEDPEIKFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGN
SDYPVEVMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=775363 PEZ79_RS10490 WP_123831403.1 2164104..2165912(-) (pepF) [Enterococcus faecium strain CQFYH22-006]
ATGGAAGTAAAGCAGTTGCCAAAACGAGAAGAATTGCCTGAAAATTTAACTTGGGACTTGACCAAGATCTTTTCAAGCGA
CCAAGAGTTTGATGAGAAATATTTGGAATTATCAGAAAAGTTAAAACAATCTGAAAAACACAAAGGAACACTTGATCAAG
GCGCTTCTCAATTTTTAAATGCGATTGAATTCGTATTGAGGGTTTATCGCCAAACTGAAGTCATTTATGTATATGCGCAC
CTTAAAAACGATCAAGACACTGGAAATACAGATTACCAAGCGCTTTATGCAAGAGCAAGCAGTCTGTTTTCGAAAGTTAG
TGAAGCCGTTTCCTGGTTTGAACCAGAAATATTGCAATTGTCAGATGACCAGATTTGGCAATATTTCAAAGAAGAACCAA
AATTGGAAGTCTATCGCCATTATATCCAGCAAATAGTAGATAATCGAGCCCATGTCTTATCTGCTGAGCAGGAATCTCTT
CTTGCTGGAGCAGGTGAAATCTTTGATGCTTCAAGTGATACATTTGCTGTTTTGAATAATGCAGATCTAGTTTTTCCAAC
GATTGAAGGAGAAAATGGTGAAATAGTCCAATTATCTCATGGCGTGTATGGTCAGTTGCTAGAAAGCACGGATCGAAGGG
TACGCGAAGCAGCATTTAAGGGATTGTACAGTGTTTACGAACAATTTAGAAATACATTTGCTTCTACTTTAGGCACACAT
ATAAAAGGACATAATTTTAAAGCGAAAGTCCGTAATTACAGCTCTGCCAGAGAAGCGTCTTTGAGCAATAATCATATTCC
TGAAAGTGTATACGATACTTTGGTAGACGTGGTAAACAAGCATTTGCCTTTGTTACATCGATACATGGAATTACGGAAAC
GTTTATTAGAAGTGGAAAAACTGCACATGTATGATCTTTATACACCGGTCTTAGGGGAAGCTCCAATTACCTTTACGTAC
GAAGAAGCAAAAGAAAAAGCTTTAGAAGCACTGAAACCAATGGGTGAAGAATACATGGCCATCGTAGAAAAAGCATTCTC
TGAACGTTGGATCGATGTTGTCGAAAATAAAGGGAAACGAAGCGGTGCTTATTCTTCGGGAAGCTATGACACAAATCCAT
ATATTTTATTGAATTGGCATGATACGCTGGATCAGCTATTTACGCTTGTCCACGAAATGGGACATAGTGTTCATAGTTAT
TTCACTCGTTCGAACCAGCCTTATGTGTACGGCGACTACTCCATCTTTTTAGCAGAAATTGCTTCGACAACGAATGAAAA
TATCCTAACGGAGTATTTATTGGAAACAGAAAAAGACCCTCGTGTACGGGCTTATGTACTCAACCATTACTTGGATGGGT
TTAAAGGAACAGTTTTCCGCCAGACACAATTCGCTGAATTCGAGCATTTCATGCATACGGAAGATGAAAAAGGTGTGCCA
TTGACTAGTGAATACCTAAGTGATAGTTATGGTAAATTGAATGCAAAATATTATGGTCCAGCAGTCGAAGAAGACCCAGA
AATTAAATTCGAATGGTCACGGATACCGCATTTTTATTATAATTACTATGTTTTCCAATACTCGACTGGCTTTTCTGCTG
CTTCAGCACTGGCGAAGAAAATACTAAACCAGGAACCAGAGGCACTAGAGAACTACTTGGCTTACCTAAAAGCAGGTAAC
AGCGATTATCCTGTGGAAGTAATGAAAAAAGCAGGAGTTGATATGACACAGGCTGCATATATCGAAGATGCAATGTCGAT
GTTTGAACAACGTCTAAATGAATTAGAAGAATTGATCGATCGTTTATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(116-185)

Peptidase family M3 (Peptidase_M3)

(206-586)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

55.649

98.505

0.548