Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   PF986_RS01210 Genome accession   NZ_CP116013
Coordinates   235573..236229 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain SRCM124349     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 230573..241229
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PF986_RS01185 (PF986_01185) oppF 231105..232022 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  PF986_RS01190 (PF986_01190) - 232129..233316 (+) 1188 WP_128974056.1 putative glycoside hydrolase -
  PF986_RS01195 (PF986_01195) - 233434..234012 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  PF986_RS01200 (PF986_01200) spx 234191..234586 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  PF986_RS01205 (PF986_01205) - 234641..235297 (-) 657 WP_123117722.1 TerC family protein -
  PF986_RS01210 (PF986_01210) mecA 235573..236229 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  PF986_RS01215 (PF986_01215) - 236380..237540 (+) 1161 WP_017417456.1 competence protein CoiA family protein -
  PF986_RS01220 (PF986_01220) pepF 237768..239597 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  PF986_RS01225 (PF986_01225) - 239635..239802 (-) 168 WP_003155026.1 hypothetical protein -
  PF986_RS01230 (PF986_01230) spxH 240088..240990 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=775162 PF986_RS01210 WP_003155032.1 235573..236229(+) (mecA) [Bacillus velezensis strain SRCM124349]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=775162 PF986_RS01210 WP_003155032.1 235573..236229(+) (mecA) [Bacillus velezensis strain SRCM124349]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895