Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QU238_RS09365 Genome accession   NZ_CP128609
Coordinates   1943623..1944279 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain HZ13     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1938623..1949279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QU238_RS09335 (QU238_09335) dcyD 1939502..1940488 (+) 987 WP_032296855.1 D-cysteine desulfhydrase -
  QU238_RS09340 (QU238_09340) tcyL 1940503..1941171 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QU238_RS09345 (QU238_09345) tcyN 1941168..1941920 (+) 753 WP_001273015.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QU238_RS09350 (QU238_09350) sdiA 1942150..1942872 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  QU238_RS09355 (QU238_09355) yecF 1942940..1943164 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QU238_RS09360 (QU238_09360) yecU 1943151..1943327 (-) 177 WP_000590344.1 protein YecU -
  QU238_RS25425 - 1943365..1943481 (-) 117 WP_001302039.1 hypothetical protein -
  QU238_RS09365 (QU238_09365) letA 1943623..1944279 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QU238_RS09370 (QU238_09370) uvrC 1944276..1946108 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QU238_RS09375 (QU238_09375) pgsA 1946165..1946713 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QU238_RS09395 (QU238_09395) yecA 1947363..1948028 (+) 666 WP_000847876.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=775025 QU238_RS09365 WP_000611328.1 1943623..1944279(+) (letA) [Escherichia coli strain HZ13]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=775025 QU238_RS09365 WP_000611328.1 1943623..1944279(+) (letA) [Escherichia coli strain HZ13]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482