Detailed information NTG0774930

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: OR232_RS06665
• Genome accession: NZ_CP128596
• Coordinates: 1359593..1362166 (+)
• Length: 857 a.a.
• NCBI ID: WP_001235102.1
• Uniprot ID: P63286
• Organism: Escherichia coli strain muskdeer13-4
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1354593..1367166

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OR232_RS06635 (OR232_006635)	pheA	1354861..1356021 (-)	1161	WP_000200124.1	bifunctional chorismate mutase/prephenate dehydratase	-
OR232_RS06640 (OR232_006640)	pheL	1356120..1356167 (-)	48	WP_001386991.1	pheA operon leader peptide PheL	-
OR232_RS06645 (OR232_006645)	raiA	1356271..1356612 (-)	342	WP_000178456.1	ribosome-associated translation inhibitor RaiA	-
OR232_RS06650 (OR232_006650)	comL	1356883..1357620 (-)	738	WP_000197686.1	outer membrane protein assembly factor BamD	Machinery gene
OR232_RS06655 (OR232_006655)	rluD	1357755..1358735 (+)	981	WP_000079112.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
OR232_RS06660 (OR232_006660)	yfiH	1358732..1359463 (+)	732	WP_000040136.1	purine nucleoside phosphorylase YfiH	-
OR232_RS06665 (OR232_006665)	clpC	1359593..1362166 (+)	2574	WP_001235102.1	ATP-dependent chaperone ClpB	Regulator

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95585.02 Da
• Isoelectric Point: 5.1899

>NTDB_id=774930 OR232_RS06665 WP_001235102.1 1359593..1362166(+) (clpC) [Escherichia coli strain muskdeer13-4]
MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGGSVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGD
VQPSQDLVRVLNLCDKLAQKRGDNFISSELFVLAALESRGTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQRQA
LKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLAL
DMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASS
IRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSDKERQYSELEEEWKAEKASLSGTQTIKAELE
QAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLL
RMEQELHHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDEAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQERFGELDYAHMKELVLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDEAL
KLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAVQ

Nucleotide

• Length: 2574 bp

>NTDB_id=774930 OR232_RS06665 WP_001235102.1 1359593..1362166(+) (clpC) [Escherichia coli strain muskdeer13-4]
ATGCGTCTGGATCGTCTTACTAATAAATTCCAGCTTGCTCTTGCCGATGCCCAATCACTTGCACTCGGGCACGACAACCA
ATTCATCGAACCACTTCATTTAATGAGCGCCCTGCTGAATCAGGAAGGGGGTTCGGTTAGTCCTTTATTAACATCCGCTG
GCATAAATGCTGGCCAGTTGCGCACAGATATCAATCAGGCATTAAATCGTTTACCGCAGGTTGAAGGTACTGGTGGTGAT
GTCCAGCCATCACAGGATCTGGTGCGCGTTCTTAATCTTTGCGACAAGCTGGCGCAAAAACGTGGTGATAACTTTATCTC
GTCAGAACTGTTCGTTCTGGCGGCACTTGAGTCTCGCGGCACGCTGGCCGACATCCTGAAAGCAGCAGGGGCGACCACCG
CCAACATTACTCAAGCGATTGAACAAATGCGTGGAGGTGAAAGCGTGAACGATCAAGGTGCTGAAGACCAACGTCAGGCT
TTGAAAAAATATACCATCGACCTTACCGAACGAGCCGAACAAGGCAAACTCGATCCGGTGATTGGTCGTGATGAAGAAAT
TCGCCGTACCATTCAGGTGCTGCAACGTCGTACTAAAAATAACCCGGTATTGATTGGTGAACCCGGCGTCGGTAAAACTG
CCATCGTTGAAGGTCTGGCGCAGCGTATTATCAACGGCGAAGTGCCCGAAGGGTTGAAAGGCCGCCGCGTACTGGCGCTG
GATATGGGCGCGCTGGTGGCTGGGGCGAAATATCGCGGTGAGTTTGAAGAACGTTTAAAAGGCGTACTTAACGATCTTGC
TAAACAGGAAGGCAACGTCATCCTGTTTATCGACGAATTACATACCATGGTCGGCGCGGGTAAAGCCGATGGCGCAATGG
ACGCCGGAAACATGCTGAAACCTGCACTGGCGCGTGGTGAATTGCACTGCGTAGGTGCCACGACGCTTGACGAATATCGC
CAGTACATCGAAAAAGATGCTGCGCTGGAACGTCGTTTCCAGAAAGTGTTTGTTGCCGAGCCTTCTGTTGAAGATACCAT
TGCTATTCTGCGTGGCCTGAAAGAACGTTACGAGCTGCACCACCATGTGCAAATTACTGACCCGGCAATTGTTGCAGCAG
CGACGTTGTCTCATCGCTACATTGCTGACCGTCAGCTGCCGGATAAAGCCATCGACCTGATCGATGAAGCAGCATCCAGC
ATTCGTATGCAGATTGACTCAAAACCAGAAGAACTCGACCGACTCGATCGTCGTATCATCCAGCTCAAACTGGAACAACA
GGCGTTAATGAAAGAGTCTGATGAAGCCAGTAAAAAACGCCTGGATATGCTCAACGAAGAACTGAGCGACAAAGAACGTC
AGTACTCCGAGTTAGAAGAAGAGTGGAAAGCAGAGAAAGCCTCGCTTTCTGGTACGCAGACCATTAAAGCGGAACTGGAA
CAGGCGAAAATCGCTATTGAACAGGCTCGCCGTGTGGGTGACCTGGCGCGGATGTCTGAACTGCAATACGGCAAAATCCC
GGAACTGGAAAAGCAACTGGAAGCCGCAACGCAGCTCGAAGGCAAAACTATGCGTCTGTTGCGTAATAAAGTGACCGATG
CCGAAATTGCTGAAGTGCTGGCGCGTTGGACGGGAATTCCGGTTTCTCGCATGATGGAAAGCGAGCGCGAAAAACTGCTG
CGTATGGAGCAAGAACTGCATCATCGCGTTATTGGTCAGAACGAAGCGGTTGATGCGGTATCTAACGCTATTCGTCGTAG
CCGTGCGGGGCTGGCGGATCCAAATCGCCCGATTGGTTCATTCCTGTTCCTCGGCCCAACGGGTGTGGGGAAAACAGAGC
TTTGTAAGGCGCTGGCGAACTTTATGTTTGATAGCGACGAGGCGATGGTCCGTATTGATATGTCCGAGTTTATGGAGAAA
CACTCGGTGTCTCGTCTGGTTGGTGCGCCTCCGGGATATGTTGGTTATGAAGAAGGTGGCTATCTGACCGAAGCGGTGCG
TCGTCGTCCGTATTCCGTCATCCTGCTGGATGAAGTGGAAAAAGCGCATCCGGATGTCTTCAACATTCTGTTGCAGGTAC
TGGATGATGGGCGTCTGACTGACGGGCAGGGGAGAACGGTCGACTTCCGTAATACGGTCGTCATTATGACCTCTAACCTC
GGTTCTGATCTGATTCAGGAACGTTTTGGTGAACTGGATTATGCGCACATGAAAGAGCTGGTGCTCGGTGTGGTAAGCCA
TAACTTCCGTCCGGAATTCATTAACCGTATCGATGAAGTCGTCGTCTTCCATCCGCTGGGTGAACAACACATTGCGTCGA
TTGCGCAGATTCAGTTGAAACGTCTGTACAAACGTCTGGAAGAACGTGGTTATGAAATCCACATTTCTGACGAGGCGCTG
AAACTGCTGAGCGAGAACGGTTACGATCCGGTCTATGGTGCACGTCCTCTGAAGCGTGCTATCCAGCAGCAGATCGAAAA
CCCGCTGGCACAGCAAATACTGTCTGGTGAATTGGTTCCGGGTAAAGTTATTCGCCTGGAAGTTAATGAAGACCGGATCG
TCGCCGTCCAGTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-443)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-337)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-760)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-845)

3D structure

• AlphaFold DB: P63286

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.816	100	0.485
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.575	100	0.428
clpE	Streptococcus pneumoniae Rx1	47.865	79.23	0.379
clpE	Streptococcus pneumoniae D39	47.865	79.23	0.379
clpE	Streptococcus pneumoniae R6	47.865	79.23	0.379
clpE	Streptococcus pneumoniae TIGR4	47.865	79.23	0.379
clpC	Lactococcus lactis subsp. cremoris KW2	46.377	80.513	0.373
clpE	Streptococcus mutans UA159	46.491	79.813	0.371