Detailed information NTG0774743

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: PE794_RS09640
• Genome accession: NZ_CP115971
• Coordinates: 2037444..2038100 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain HBS1
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2032444..2043100

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PE794_RS09620 (PE794_09620)	nanA	2032818..2033696 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
PE794_RS09625 (PE794_09625)	nagB	2033746..2034549 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
PE794_RS09630 (PE794_09630)	nagA	2034601..2035746 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
PE794_RS09635 (PE794_09635)	fumC	2035895..2037289 (-)	1395	WP_005599273.1	class II fumarate hydratase	-
PE794_RS09640 (PE794_09640)	sxy/tfoX	2037444..2038100 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
PE794_RS09645 (PE794_09645)	rpsJ	2038508..2038819 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
PE794_RS09650 (PE794_09650)	rplC	2038845..2039471 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
PE794_RS09655 (PE794_09655)	rplD	2039487..2040089 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
PE794_RS09660 (PE794_09660)	rplW	2040086..2040391 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
PE794_RS09665 (PE794_09665)	rplB	2040412..2041233 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
PE794_RS09670 (PE794_09670)	rpsS	2041261..2041536 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
PE794_RS09675 (PE794_09675)	rplV	2041547..2041879 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
PE794_RS09680 (PE794_09680)	rpsC	2041898..2042605 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
PE794_RS09685 (PE794_09685)	rplP	2042619..2043029 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=774743 PE794_RS09640 WP_005609196.1 2037444..2038100(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain HBS1]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=774743 PE794_RS09640 WP_005609196.1 2037444..2038100(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain HBS1]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376