Detailed information NTG0077329

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: H7R41_RS18415
• Genome accession: NZ_AP022238
• Coordinates: 3385700..3386560 (+)
• Length: 286 a.a.
• NCBI ID: WP_001152268.1
• Uniprot ID: A0A1E3M8A8
• Organism: Acinetobacter baumannii strain WP8-W18-ESBL-11
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3380700..3391560

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7R41_RS15910 (WP8W18E11_31180)	secG	3381305..3381634 (-)	330	WP_000555570.1	preprotein translocase subunit SecG	-
H7R41_RS15915 (WP8W18E11_31190)	tpiA	3381647..3382441 (-)	795	WP_000016939.1	triose-phosphate isomerase	-
H7R41_RS15920 (WP8W18E11_31200)	pilB	3382732..3384444 (+)	1713	WP_001274983.1	type IV-A pilus assembly ATPase PilB	Machinery gene
H7R41_RS15925 (WP8W18E11_31210)	pilC	3384474..3385700 (+)	1227	WP_000279216.1	type II secretion system F family protein	Machinery gene
H7R41_RS18415 (WP8W18E11_31220)	pilD	3385700..3386560 (+)	861	WP_001152268.1	A24 family peptidase	Machinery gene
H7R41_RS15935 (WP8W18E11_31230)	coaE	3386562..3387158 (+)	597	WP_000874127.1	dephospho-CoA kinase	-
H7R41_RS15940 (WP8W18E11_31240)	-	3387155..3388072 (-)	918	WP_000075016.1	DMT family transporter	-
H7R41_RS15945 (WP8W18E11_31250)	rlmB	3388108..3388857 (-)	750	WP_001118149.1	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	-
H7R41_RS15950 (WP8W18E11_31260)	-	3388959..3389285 (-)	327	WP_000099685.1	pyrimidine/purine nucleoside phosphorylase	-
H7R41_RS15955 (WP8W18E11_31270)	-	3389362..3390672 (-)	1311	WP_000753297.1	tetratricopeptide repeat protein	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 32094.47 Da
• Isoelectric Point: 7.1041

>NTDB_id=77329 H7R41_RS18415 WP_001152268.1 3385700..3386560(+) (pilD) [Acinetobacter baumannii strain WP8-W18-ESBL-11]
MQDIIAYFIQNFTALYIAVALVSLCIGSFLNVVIYRTPKMMEQDWQQECQMLLNPEQPIIDHEKLTLSKPASSCPACQQP
IRWYQNIPVISWLVLRGKCGHCQHPISIRYPAIELLTMLCSLVVVMVFGPTIQMLFGLVLTWVLIALTFIDFDTQLLPDR
FTLTLAALGLGINTFNIYTSPNSAIWGYLIGFLCLWIVYYLFKVITGKEGMGYGDFKLLAALGAWMGPLMLPLIVLLSSL
LGAIIGIILLKLRNDNQPFAFGPYIAIAGWVAFLWGDQIMKIYLGG

Nucleotide

• Length: 861 bp

>NTDB_id=77329 H7R41_RS18415 WP_001152268.1 3385700..3386560(+) (pilD) [Acinetobacter baumannii strain WP8-W18-ESBL-11]
ATGCAAGACATCATTGCGTATTTTATTCAAAACTTTACTGCACTTTATATTGCTGTTGCACTCGTGAGCCTATGTATCGG
TAGCTTTCTTAATGTAGTGATTTACCGCACGCCAAAAATGATGGAGCAAGATTGGCAGCAAGAATGCCAAATGCTGCTCA
ATCCTGAGCAACCCATTATTGATCATGAGAAGTTAACTTTAAGTAAGCCTGCTTCATCGTGCCCTGCATGTCAGCAACCG
ATCCGTTGGTATCAAAATATTCCTGTTATAAGCTGGCTTGTGTTAAGAGGAAAATGTGGTCATTGCCAGCACCCGATTAG
TATTCGCTATCCAGCCATCGAACTACTCACCATGCTATGTTCATTAGTAGTAGTCATGGTATTTGGCCCAACCATACAAA
TGCTTTTTGGACTCGTCCTCACATGGGTACTGATAGCCCTTACCTTTATTGATTTCGATACACAATTATTGCCTGATCGC
TTTACCCTAACTTTAGCTGCGCTCGGCTTAGGTATTAATACCTTTAATATTTATACCTCACCCAACTCAGCCATTTGGGG
TTATCTCATTGGTTTCCTATGTCTTTGGATTGTCTATTACTTATTTAAAGTGATCACTGGTAAAGAAGGTATGGGCTACG
GCGACTTTAAATTGCTTGCAGCATTAGGAGCATGGATGGGGCCATTGATGCTGCCGTTAATTGTGTTATTGTCATCGTTA
CTTGGCGCAATCATTGGCATCATTTTATTAAAATTAAGAAATGACAATCAGCCTTTTGCTTTTGGGCCATATATTGCCAT
TGCTGGTTGGGTTGCCTTTTTATGGGGTGATCAGATTATGAAAATTTATTTGGGAGGTTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (138-247)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (22-128)

3D structure

• AlphaFold DB: A0A1E3M8A8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Acinetobacter baumannii D1279779	98.601	100	0.986
pilD	Acinetobacter nosocomialis M2	98.252	100	0.983
pilD	Vibrio cholerae strain A1552	53.875	94.755	0.51
pilD	Vibrio campbellii strain DS40M4	51.971	97.552	0.507
pilD	Neisseria gonorrhoeae MS11	47.348	92.308	0.437