Detailed information NTG0077303

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: H7R41_RS04290
• Genome accession: NZ_AP022238
• Coordinates: 909434..911866 (+)
• Length: 810 a.a.
• NCBI ID: WP_000472702.1
• Uniprot ID: A0A1E3MCU2
• Organism: Acinetobacter baumannii strain WP8-W18-ESBL-11
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 904434..916866

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7R41_RS04265 (WP8W18E11_08120)	-	904584..905525 (-)	942	WP_000795877.1	hypothetical protein	-
H7R41_RS04270 (WP8W18E11_08130)	-	905782..906267 (+)	486	WP_001985538.1	YaiI/YqxD family protein	-
H7R41_RS04275 (WP8W18E11_08140)	-	906278..907186 (+)	909	WP_001140078.1	DMT family transporter	-
H7R41_RS18440	-	907216..907296 (-)	81	Protein_815	PilZ domain-containing protein	-
H7R41_RS04280 (WP8W18E11_08150)	-	907434..908669 (+)	1236	WP_001984636.1	lipoprotein-releasing ABC transporter permease subunit	-
H7R41_RS04285 (WP8W18E11_08160)	lolD	908662..909348 (+)	687	WP_000049406.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
H7R41_RS04290 (WP8W18E11_08170)	comA/comEC	909434..911866 (+)	2433	WP_000472702.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H7R41_RS04295 (WP8W18E11_08180)	-	911819..912802 (-)	984	WP_001984639.1	lysophospholipid acyltransferase family protein	-
H7R41_RS04300 (WP8W18E11_08190)	sppA	912935..913951 (+)	1017	WP_001286612.1	signal peptide peptidase SppA	-
H7R41_RS04305 (WP8W18E11_08200)	-	913970..914779 (+)	810	WP_000114071.1	alpha/beta fold hydrolase	-
H7R41_RS04310 (WP8W18E11_08210)	purN	914843..915472 (-)	630	WP_000975525.1	phosphoribosylglycinamide formyltransferase	-
H7R41_RS04315 (WP8W18E11_08220)	purM	915469..916539 (-)	1071	WP_000071984.1	phosphoribosylformylglycinamidine cyclo-ligase	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 92486.72 Da
• Isoelectric Point: 8.5374

>NTDB_id=77303 H7R41_RS04290 WP_000472702.1 909434..911866(+) (comA/comEC) [Acinetobacter baumannii strain WP8-W18-ESBL-11]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGEALLLLAFIFYLYKRPMFVDRPFLKAVFCLLCTTSLFMVGYHYAEKALIE
RLEQRETDTRNLDIIVYINHLSEEKDNKVQQTAQVLNLSKEPVNWLLYLKSNNQNLLKNNQNLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIVSSFNVRYIEPLSLDEIYRLGYQQHLKEQQSFSNSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYYPQIYLWKPKQILMAVPCCLGVLIYTA
FVGFEIPALRTLLSVFIFIGFLLLKQPIKPFTLLVYSASLLLLIDPFSVFSAGFWLSYGACFILLRIYQTIAQLPEQHFL
SLSSKMIFMSKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGGVIVPLNIMAACAWFVIKPFGNMLFHFND
MLLSILLSCLGLLEKLSLPLQGISLTPLSLLAISFAIIILFLPKGILPKTWGILCCLPLVIMNKTSQQIQLNILDVGQGQ
AIFLQHSEQNWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDHSGAFPLIQQEIPVKQLISNEQLPND
LKQPFQYCHQGQQWHYPELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVGGYQNFLIMGDAGWEAEYELLKDYPNLK
IDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTVEQGTLSFVLENHKIVLHDRR
LDRLWLSRGF

Nucleotide

• Length: 2433 bp

>NTDB_id=77303 H7R41_RS04290 WP_000472702.1 909434..911866(+) (comA/comEC) [Acinetobacter baumannii strain WP8-W18-ESBL-11]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCGAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGCCCCATGTTCGTTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAACAAGTCTTTTTATGGTTGGTTACCACTATGCTGAAAAAGCATTGATTGAA
CGATTAGAACAAAGAGAAACGGATACCCGAAATCTCGACATTATTGTTTATATAAACCATTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATCTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGAATCTTGAATTAGGCCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAGTGGTTTATTCAGCGAAATATTGTGTCTAGTTTTAACGTGAGATATAT
TGAGCCTTTAAGTCTCGATGAAATCTATCGATTGGGCTATCAGCAACATTTAAAAGAACAACAGTCTTTTTCCAATAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTCTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGCCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTAGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATCAGTCGTTATT
ATCCTCAAATTTACTTATGGAAACCGAAACAGATTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAGTATTTATATTTATTGGATTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTCGTATATAGCGCAAGTCTACTGTTGCTAATTGACCCGTTTAGTGTGTTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGCTTTATTTTATTAAGAATTTACCAAACTATAGCGCAGCTACCTGAGCAACATTTTTTA
AGTCTGAGCTCAAAAATGATTTTTATGAGTAAGGTGTTAATTGAATCTCAAGGCAAAATATTTATTGCATTGAGTCCCTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGTGGTGTTA
TTGTCCCTTTAAACATCATGGCTGCTTGCGCATGGTTTGTAATAAAACCATTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGCATATTGCTGAGTTGTTTGGGCTTATTAGAAAAACTCTCTTTACCATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTTTGCCATAATTATTTTATTTTTACCTAAAGGAATTTTGCCCAAAACTTGGGGGATAT
TATGTTGTTTACCCTTAGTTATTATGAACAAAACGAGTCAGCAAATTCAGCTTAATATTTTAGATGTTGGACAGGGGCAA
GCCATTTTTTTACAACATTCCGAACAAAACTGGTTAATTGATACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAATTAGATCATGTTGTGCTATCCCATCTTGATCAAG
ACCATAGTGGCGCGTTTCCTCTTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAATGAT
TTAAAGCAACCATTCCAATATTGCCATCAAGGGCAACAATGGCATTATCCTGAGTTAGATATTCAAATTTTATGGCCTAA
AGAAAAAGATCTGGCTTTTGTTGCTTCTAACCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTGGTG
GTTACCAAAATTTTCTTATTATGGGCGATGCTGGATGGGAAGCTGAATACGAGTTATTAAAAGATTATCCTAACTTGAAG
ATAGATGTGTTAGTGCTAGGGCATCATGGAAGTAAGCACAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAAACT
GGCCATTGCATCGGCAGGGTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTACATA
TTCCGCTAAAAAGCACTGTGGAACAAGGGACCTTAAGTTTTGTGTTGGAAAATCACAAAATAGTTTTACATGACCGACGT
TTGGATAGGCTCTGGTTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-639)

• Domain of unknown function (DUF4131) (DUF4131) (33-188)

• Competence protein (Competence) (243-521)

3D structure

• AlphaFold DB: A0A1E3MCU2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	98.148	100	0.981
comA/comEC	Acinetobacter baumannii strain A118	97.037	100	0.97
comA/comEC	Acinetobacter baylyi ADP1	50.308	100	0.504