Detailed information NTG0772502

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: PDI73_RS09195
• Genome accession: NZ_CP115479
• Coordinates: 1897963..1898991 (-)
• Length: 342 a.a.
• NCBI ID: WP_003132657.1
• Uniprot ID: S6FVM6
• Organism: Lactococcus lactis strain EP2
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1892963..1903991

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PDI73_RS09165 (PDI73_09165)	-	1893222..1893944 (-)	723	WP_033900892.1	ABC transporter permease	-
PDI73_RS09170 (PDI73_09170)	-	1893946..1894818 (-)	873	WP_277730165.1	ABC transporter ATP-binding protein	-
PDI73_RS09175 (PDI73_09175)	-	1894802..1896067 (-)	1266	WP_033900888.1	radical SAM protein	-
PDI73_RS09180 (PDI73_09180)	-	1896064..1896657 (-)	594	WP_277730166.1	hypothetical protein	-
PDI73_RS09185 (PDI73_09185)	-	1896712..1896867 (-)	156	WP_012898304.1	hypothetical protein	-
PDI73_RS09190 (PDI73_09190)	-	1896986..1897843 (-)	858	WP_033900885.1	Rgg/GadR/MutR family transcriptional regulator	-
PDI73_RS09195 (PDI73_09195)	sepM	1897963..1898991 (-)	1029	WP_003132657.1	SepM family pheromone-processing serine protease	Regulator
PDI73_RS09200 (PDI73_09200)	coaD	1898978..1899475 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
PDI73_RS09205 (PDI73_09205)	rsmD	1899523..1900062 (-)	540	WP_015427191.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
PDI73_RS09210 (PDI73_09210)	-	1900233..1901453 (-)	1221	WP_012898647.1	MFS transporter	-
PDI73_RS09215 (PDI73_09215)	lmrP	1901537..1902763 (-)	1227	WP_033900880.1	multidrug efflux MFS transporter LmrP	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37349.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=772502 PDI73_RS09195 WP_003132657.1 1897963..1898991(-) (sepM) [Lactococcus lactis strain EP2]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=772502 PDI73_RS09195 WP_003132657.1 1897963..1898991(-) (sepM) [Lactococcus lactis strain EP2]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTACCCAACAAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTTCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAGCTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGTAAAACAGGAATAGGGA
TTAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCGAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
GACGATTGAACACGACGGAAGCATTGGTCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGTAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

3D structure

• AlphaFold DB: S6FVM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491