Detailed information NTG0772455

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: PDI59_RS12995
• Genome accession: NZ_CP115478
• Coordinates: 2576729..2577616 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain HP20814-062
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2571729..2582616

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PDI59_RS12965 (PDI59_12965)	-	2571748..2571840 (+)	93	WP_010956583.1	hypothetical protein	-
PDI59_RS12970 (PDI59_12970)	-	2571948..2572445 (-)	498	WP_001065268.1	glutathione peroxidase	-
PDI59_RS12975 (PDI59_12975)	-	2572455..2572715 (-)	261	WP_001791974.1	hypothetical protein	-
PDI59_RS12980 (PDI59_12980)	-	2573097..2573210 (-)	114	Protein_2518	hypothetical protein	-
PDI59_RS12985 (PDI59_12985)	-	2573869..2575869 (-)	2001	WP_000776750.1	ABC transporter permease	-
PDI59_RS12990 (PDI59_12990)	-	2575866..2576621 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
PDI59_RS12995 (PDI59_12995)	braS	2576729..2577616 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
PDI59_RS13000 (PDI59_13000)	braR	2577627..2578292 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
PDI59_RS13005 (PDI59_13005)	-	2578318..2578518 (-)	201	WP_000604730.1	hypothetical protein	-
PDI59_RS13010 (PDI59_13010)	-	2578716..2580140 (+)	1425	WP_000953755.1	alkaline phosphatase	-
PDI59_RS14400	-	2580200..2580301 (-)	102	WP_000731976.1	SE2200 family small protein	-
PDI59_RS13020 (PDI59_13020)	-	2580423..2580878 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
PDI59_RS13025 (PDI59_13025)	-	2581123..2581884 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=772455 PDI59_RS12995 WP_000143425.1 2576729..2577616(-) (braS) [Staphylococcus aureus strain HP20814-062]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=772455 PDI59_RS12995 WP_000143425.1 2576729..2577616(-) (braS) [Staphylococcus aureus strain HP20814-062]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1