Detailed information NTG0772416

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: PDI55_RS13855
• Genome accession: NZ_CP115477
• Coordinates: 2765043..2765930 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain HP20814-043
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2760043..2770930

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PDI55_RS13825 (PDI55_13825)	-	2760062..2760154 (+)	93	WP_010956583.1	hypothetical protein	-
PDI55_RS13830 (PDI55_13830)	-	2760262..2760759 (-)	498	WP_001065268.1	glutathione peroxidase	-
PDI55_RS13835 (PDI55_13835)	-	2760769..2761029 (-)	261	WP_001791974.1	hypothetical protein	-
PDI55_RS13840 (PDI55_13840)	-	2761411..2761524 (-)	114	Protein_2692	hypothetical protein	-
PDI55_RS13845 (PDI55_13845)	-	2762183..2764183 (-)	2001	WP_000776750.1	ABC transporter permease	-
PDI55_RS13850 (PDI55_13850)	-	2764180..2764935 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
PDI55_RS13855 (PDI55_13855)	braS	2765043..2765930 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
PDI55_RS13860 (PDI55_13860)	braR	2765941..2766606 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
PDI55_RS13865 (PDI55_13865)	-	2766632..2766832 (-)	201	WP_000604730.1	hypothetical protein	-
PDI55_RS13870 (PDI55_13870)	-	2767030..2768454 (+)	1425	WP_000953755.1	alkaline phosphatase	-
PDI55_RS14340	-	2768514..2768615 (-)	102	WP_000731976.1	SE2200 family small protein	-
PDI55_RS13880 (PDI55_13880)	-	2768737..2769192 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
PDI55_RS13885 (PDI55_13885)	-	2769437..2770198 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=772416 PDI55_RS13855 WP_000143425.1 2765043..2765930(-) (braS) [Staphylococcus aureus strain HP20814-043]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=772416 PDI55_RS13855 WP_000143425.1 2765043..2765930(-) (braS) [Staphylococcus aureus strain HP20814-043]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1