Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | PDI56_RS10275 | Genome accession | NZ_CP115473 |
| Coordinates | 2044668..2046296 (+) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain AF4004 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2007792..2051517 | 2044668..2046296 | within | 0 |
| SCCmec | 2043297..2064662 | 2044668..2046296 | within | 0 |
Gene organization within MGE regions
Location: 2007792..2064662
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PDI56_RS10115 (PDI56_10115) | - | 2007792..2010944 (-) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
| PDI56_RS10120 (PDI56_10120) | - | 2011211..2011813 (-) | 603 | WP_000908956.1 | hypothetical protein | - |
| PDI56_RS10125 (PDI56_10125) | - | 2012021..2012317 (-) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| PDI56_RS10130 (PDI56_10130) | - | 2012366..2012569 (-) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| PDI56_RS10135 (PDI56_10135) | - | 2012878..2013864 (+) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| PDI56_RS14425 | - | 2014050..2014264 (+) | 215 | Protein_1965 | universal stress protein | - |
| PDI56_RS10145 (PDI56_10145) | sqr | 2014531..2015724 (-) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| PDI56_RS10150 (PDI56_10150) | cstB | 2015743..2017077 (-) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| PDI56_RS10155 (PDI56_10155) | cstA | 2017108..2018172 (-) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| PDI56_RS10160 (PDI56_10160) | cstR | 2018309..2018569 (+) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| PDI56_RS10165 (PDI56_10165) | - | 2018569..2019324 (+) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| PDI56_RS10170 (PDI56_10170) | - | 2019422..2019510 (+) | 89 | Protein_1971 | hypothetical protein | - |
| PDI56_RS10175 (PDI56_10175) | - | 2019815..2020170 (+) | 356 | Protein_1972 | tRNA-dihydrouridine synthase | - |
| PDI56_RS10180 (PDI56_10180) | - | 2020268..2022013 (-) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| PDI56_RS10185 (PDI56_10185) | - | 2022160..2022252 (-) | 93 | WP_001790000.1 | hypothetical protein | - |
| PDI56_RS10190 (PDI56_10190) | - | 2022216..2022350 (+) | 135 | WP_001790628.1 | hypothetical protein | - |
| PDI56_RS10195 (PDI56_10195) | - | 2022600..2024108 (-) | 1509 | WP_001001347.1 | protein kinase | - |
| PDI56_RS10200 (PDI56_10200) | - | 2024223..2024849 (+) | 627 | WP_001176969.1 | hypothetical protein | - |
| PDI56_RS10205 (PDI56_10205) | - | 2025968..2026864 (+) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| PDI56_RS10210 (PDI56_10210) | - | 2026874..2027743 (+) | 870 | WP_000626133.1 | hypothetical protein | - |
| PDI56_RS10215 (PDI56_10215) | - | 2028288..2028845 (-) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| PDI56_RS10220 (PDI56_10220) | - | 2028861..2030882 (-) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| PDI56_RS10225 (PDI56_10225) | kdpA | 2030901..2032577 (-) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| PDI56_RS14430 | kdpF | 2032598..2032678 (-) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| PDI56_RS10230 (PDI56_10230) | - | 2032845..2035514 (+) | 2670 | WP_000446429.1 | sensor histidine kinase KdpD | - |
| PDI56_RS10235 (PDI56_10235) | - | 2035489..2036184 (+) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| PDI56_RS10240 (PDI56_10240) | - | 2036906..2037832 (+) | 927 | Protein_1986 | YfcC family protein | - |
| PDI56_RS10245 (PDI56_10245) | - | 2038039..2038173 (-) | 135 | WP_001792216.1 | hypothetical protein | - |
| PDI56_RS10250 (PDI56_10250) | - | 2038343..2039484 (+) | 1142 | Protein_1988 | IS3-like element ISSau4 family transposase | - |
| PDI56_RS10255 (PDI56_10255) | - | 2039735..2040781 (+) | 1047 | WP_001060127.1 | hypothetical protein | - |
| PDI56_RS10260 (PDI56_10260) | - | 2040974..2041270 (+) | 297 | WP_000273824.1 | single-stranded DNA-binding protein | - |
| PDI56_RS10265 (PDI56_10265) | - | 2041270..2043063 (+) | 1794 | WP_000195105.1 | DUF927 domain-containing protein | - |
| PDI56_RS10270 (PDI56_10270) | ccrA | 2043297..2044646 (+) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| PDI56_RS10275 (PDI56_10275) | ccrB | 2044668..2046296 (+) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| PDI56_RS10280 (PDI56_10280) | - | 2046814..2047164 (+) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| PDI56_RS10285 (PDI56_10285) | - | 2047251..2047562 (+) | 312 | WP_000700853.1 | DUF960 family protein | - |
| PDI56_RS10290 (PDI56_10290) | - | 2047580..2048086 (+) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| PDI56_RS10295 (PDI56_10295) | - | 2048107..2048424 (+) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| PDI56_RS10300 (PDI56_10300) | - | 2048543..2049628 (+) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| PDI56_RS10305 (PDI56_10305) | - | 2049625..2051517 (+) | 1893 | WP_001557544.1 | site-specific integrase | - |
| PDI56_RS10310 (PDI56_10310) | - | 2051524..2051901 (+) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| PDI56_RS10315 (PDI56_10315) | - | 2052052..2052834 (+) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| PDI56_RS10320 (PDI56_10320) | erm(A) | 2052960..2053691 (-) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| PDI56_RS14435 | - | 2053774..2053833 (-) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| PDI56_RS10325 (PDI56_10325) | - | 2054225..2054887 (+) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| PDI56_RS10330 (PDI56_10330) | - | 2055232..2055870 (-) | 639 | Protein_2005 | sulfite exporter TauE/SafE family protein | - |
| PDI56_RS10335 (PDI56_10335) | cstR | 2055870..2056130 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| PDI56_RS10340 (PDI56_10340) | - | 2056266..2057330 (+) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| PDI56_RS10345 (PDI56_10345) | cstB | 2057363..2058697 (+) | 1335 | Protein_2008 | persulfide dioxygenase-sulfurtransferase CstB | - |
| PDI56_RS10350 (PDI56_10350) | - | 2058811..2059920 (-) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| PDI56_RS10355 (PDI56_10355) | psm-mec | 2060275..2060343 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| PDI56_RS10360 (PDI56_10360) | mecI | 2060428..2060799 (-) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| PDI56_RS10365 (PDI56_10365) | mecR1 | 2060799..2062556 (-) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| PDI56_RS10370 (PDI56_10370) | mecA | 2062653..2064662 (+) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=772278 PDI56_RS10275 WP_001186602.1 2044668..2046296(+) (ccrB) [Staphylococcus aureus strain AF4004]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=772278 PDI56_RS10275 WP_001186602.1 2044668..2046296(+) (ccrB) [Staphylococcus aureus strain AF4004]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |