Detailed information NTG0771368

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: PCP81_RS12375
• Genome accession: NZ_CP115288
• Coordinates: 2646015..2648240 (-)
• Length: 741 a.a.
• NCBI ID: WP_003119806.1
• Uniprot ID: A0A1S1C5Z8
• Organism: Pseudomonas aeruginosa strain F005
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2641015..2653240

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PCP81_RS12340 (PCP81_12335)	murB	2641405..2642424 (-)	1020	WP_003118084.1	UDP-N-acetylmuramate dehydrogenase	-
PCP81_RS12345 (PCP81_12340)	-	2642421..2642885 (-)	465	WP_003091154.1	low molecular weight protein-tyrosine-phosphatase	-
PCP81_RS12350 (PCP81_12345)	kdsB	2642885..2643649 (-)	765	WP_003091155.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
PCP81_RS12355 (PCP81_12350)	-	2643649..2643834 (-)	186	WP_003091157.1	Trm112 family protein	-
PCP81_RS12360 (PCP81_12355)	lpxK	2643872..2644870 (-)	999	WP_003091159.1	tetraacyldisaccharide 4'-kinase	-
PCP81_RS12365 (PCP81_12360)	-	2644870..2645310 (-)	441	WP_003091161.1	ExbD/TolR family protein	-
PCP81_RS12370 (PCP81_12365)	exbB	2645307..2645942 (-)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
PCP81_RS12375 (PCP81_12370)	comA	2646015..2648240 (-)	2226	WP_003119806.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
PCP81_RS12380 (PCP81_12375)	-	2648371..2648904 (+)	534	WP_003091165.1	DUF2062 domain-containing protein	-
PCP81_RS12385 (PCP81_12380)	-	2648992..2650236 (-)	1245	WP_003118085.1	lipoprotein-releasing ABC transporter permease subunit	-
PCP81_RS12390 (PCP81_12385)	lolD	2650306..2650989 (-)	684	WP_003118086.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
PCP81_RS12395 (PCP81_12390)	-	2650982..2652232 (-)	1251	WP_003091170.1	lipoprotein-releasing ABC transporter permease subunit	-
PCP81_RS12400 (PCP81_12395)	-	2652335..2652934 (+)	600	WP_003105196.1	PilZ domain-containing protein	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 80048.70 Da
• Isoelectric Point: 10.5155

>NTDB_id=771368 PCP81_RS12375 WP_003119806.1 2646015..2648240(-) (comA) [Pseudomonas aeruginosa strain F005]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVRAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GTVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLATLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHVLLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPVWLVSGEPARLPSPLFADSCDERSWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
LLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=771368 PCP81_RS12375 WP_003119806.1 2646015..2648240(-) (comA) [Pseudomonas aeruginosa strain F005]
ATGCGCCTGGGATTGCCAGCCCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCCGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCACGGTGAAGGCGGGCCAGCGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGCCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGGTTGAGCGCGGCCGAGT
GGCGAATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCGGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCCTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGCGCCTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGCAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCGGGGAGCCTGCTGCTATGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCGCTTGGCCTGCTGGCGGGCCTGGCCGAGGCCTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCATTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGAGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGAGAGCATGTCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGTTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGAGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCACAGGCCGGCG
ACAGCAACGACCGCTCCTGTGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCCCGGGTCGACTGGTTGCTGGCGCCGCATCATGGCAGCCGCAGTTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGGCCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAGCGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
CTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: A0A1S1C5Z8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	58.807	97.301	0.572
comA	Ralstonia pseudosolanacearum GMI1000	35.48	100	0.364