Detailed information NTG0769591

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: F6I26_RS10540
• Genome accession: NZ_CP126961
• Coordinates: 2046407..2048968 (-)
• Length: 853 a.a.
• NCBI ID: WP_150888279.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain UMB4708
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2041407..2053968

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F6I26_RS10505 (F6I26_010505)	-	2042183..2042488 (+)	306	WP_224784148.1	hypothetical protein	-
F6I26_RS10510 (F6I26_010510)	-	2042648..2043091 (+)	444	WP_024053143.1	DUF1492 domain-containing protein	-
F6I26_RS10515 (F6I26_010515)	-	2043139..2043717 (+)	579	WP_024053142.1	hypothetical protein	-
F6I26_RS10520 (F6I26_010520)	-	2043717..2044052 (+)	336	WP_041326062.1	hypothetical protein	-
F6I26_RS11130	-	2044181..2044384 (+)	204	Protein_2035	hypothetical protein	-
F6I26_RS10525 (F6I26_010525)	-	2044733..2044852 (+)	120	Protein_2036	phage terminase small subunit P27 family	-
F6I26_RS10530 (F6I26_010530)	-	2045323..2045763 (+)	441	WP_070242129.1	LytTR family DNA-binding domain-containing protein	-
F6I26_RS10535 (F6I26_010535)	-	2045760..2046218 (+)	459	WP_024053227.1	DUF3021 domain-containing protein	-
F6I26_RS10540 (F6I26_010540)	hexA	2046407..2048968 (-)	2562	WP_150888279.1	DNA mismatch repair protein MutS	Machinery gene
F6I26_RS10545 (F6I26_010545)	argR	2049339..2049779 (-)	441	WP_150888281.1	arginine repressor	-
F6I26_RS10550 (F6I26_010550)	argS	2049883..2051571 (+)	1689	WP_150888283.1	arginine--tRNA ligase	-
F6I26_RS10555 (F6I26_010555)	nrdI	2051626..2052081 (-)	456	WP_024053230.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
F6I26_RS10560 (F6I26_010560)	-	2052157..2052666 (-)	510	WP_150888285.1	hypothetical protein	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 96083.84 Da
• Isoelectric Point: 5.0405

>NTDB_id=769591 F6I26_RS10540 WP_150888279.1 2046407..2048968(-) (hexA) [Streptococcus anginosus strain UMB4708]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDATNAAQILEIALTSRNKNSENPIPMAGVPYHSVQQYIDVLI
EAGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDKLSGIYGLAYMDVGTGEFQVTSLSDFNI
VCGEIRNLRAREVVLGYELSEMERQVLETQMNLLLSQVETTFDDVQLLGKDLSPLERQVAGKLLQYVHKTQLRELSHLKQ
VHHYEIKDFLQMDYSTMASLDLIENARTGKKRGSLYWLMDETKTAMGTRLLRAWIQRPLIDKERIVKRQDVVQVFLDHFF
ERSDLSDSLKGVYDIERLASRVSFGKTNPKDLLQLAATLSHVPQIKGILKGIDSPVLEDLIAKLDEIPELASLIQSAISP
DAPNVITEGNIIKTGFDETLDKYRVVIRDGTSWIADIEAKEREASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQSLAQTMATVDVLQSFAAVAEKQHFVRPEFI
EQRSIQIDKGRHAVVEKVMGAQTYIPNSISMDENVNVQLITGPNMSGKSTYMRQLAIVVIMAQMGSYVSAESAQLPIFDA
IFTRIGAADDLVSGQSTFMIEMMEANHAISQATENSLILFDELGRGTATYDGMALAQAIIEYIHNRTGAKTLFATHYHEL
TELSTSLTQLENVHVATLEKDGQVTFLHKIEVGPADKSYGLHVAKIAGLPNDLLTRADQILTRLESQVNEKPSFGIFNTL
PADAREKNQVAEQMSLFTETTESPILDELRQLDIYNMTPMEVMLAVAEIKKKL

Nucleotide

• Length: 2562 bp

>NTDB_id=769591 F6I26_RS10540 WP_150888279.1 2046407..2048968(-) (hexA) [Streptococcus anginosus strain UMB4708]
ATGACAAAAGAAAAACTATCTCCAGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCAGATGCTTTTTTGTTGTT
TCGCATGGGAGATTTTTATGAATTATTCTATGATGATGCGACCAATGCGGCACAGATTTTAGAGATTGCTCTGACTAGTC
GCAATAAAAACTCGGAAAATCCAATCCCAATGGCAGGAGTTCCTTACCATTCAGTGCAGCAATACATTGATGTTTTAATT
GAAGCAGGCTATAAAGTTGCGATTGCAGAGCAAATGGAAGATCCTAAAAAAGCGGTTGGAGTAGTCAAACGCGAAGTAGT
ACAGGTGATTACGCCGGGGACAGTAGTTGATTCTTCAAAACCAGACAGTCAGAATAACTTTTTAGTGGCTTTGGATAAGC
TGTCAGGTATATATGGACTGGCTTATATGGATGTGGGAACGGGTGAATTTCAGGTCACAAGTCTTAGTGACTTTAACATA
GTCTGTGGAGAAATCCGAAACCTGCGAGCGCGTGAAGTGGTCTTAGGGTATGAATTGTCTGAAATGGAGCGCCAAGTATT
GGAGACTCAAATGAATCTCCTTTTATCGCAAGTAGAAACTACATTTGATGATGTTCAGCTACTAGGAAAGGACTTGTCGC
CGCTAGAGCGCCAAGTAGCTGGAAAGTTATTACAGTATGTTCATAAAACGCAGCTACGTGAGCTTAGTCATTTGAAACAA
GTTCATCATTATGAAATCAAAGATTTCTTGCAGATGGACTACTCAACTATGGCAAGTCTGGATTTAATAGAGAATGCTCG
AACAGGAAAGAAGCGCGGGAGCCTTTATTGGCTGATGGATGAGACTAAGACAGCTATGGGAACACGATTGTTGAGAGCGT
GGATTCAACGTCCGTTGATTGATAAAGAGCGGATCGTCAAGCGGCAGGATGTAGTGCAAGTCTTTTTAGATCATTTCTTT
GAGCGCAGTGACTTATCAGACAGTCTCAAAGGAGTGTATGATATTGAGCGTTTAGCCAGTCGGGTTTCGTTTGGCAAGAC
CAATCCGAAAGATCTATTACAACTTGCTGCGACATTGAGTCATGTGCCACAAATTAAGGGAATTTTAAAAGGAATTGATA
GCCCAGTTTTGGAAGATTTGATTGCAAAATTGGATGAAATTCCTGAACTGGCGTCCTTAATTCAGTCAGCAATTTCGCCG
GATGCTCCAAATGTCATTACAGAGGGTAATATTATTAAAACAGGTTTTGATGAAACCTTGGATAAATATCGAGTGGTTAT
ACGAGATGGAACGAGCTGGATTGCAGATATTGAGGCGAAAGAAAGAGAAGCTAGTGGAATTAACAACCTGAAGATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTCACAAATTCCCAGCTTGAACACGTTCCCAGTCATTTTTTCCGCAAGGCA
ACTCTGAAAAATTCAGAGCGTTTTGGTACGGAAGAACTGGCTCGTATTGAAGGGGAGATGTTGGAAGCGCGTGAAAAATC
AGCTAATTTGGAATACGAGATTTTTATGCGCATTCGTGAGGAAGCTGGTAAATATATCAAACGCCTGCAATCCTTGGCGC
AAACTATGGCAACAGTTGATGTGCTGCAAAGCTTTGCAGCTGTAGCTGAAAAGCAACACTTTGTGAGACCAGAATTTATT
GAGCAGCGCTCTATCCAAATTGATAAAGGGCGGCATGCGGTCGTAGAAAAAGTTATGGGTGCACAAACCTATATTCCTAA
TAGCATTTCAATGGATGAGAATGTTAATGTTCAGCTAATTACAGGCCCAAATATGAGTGGGAAGTCAACTTATATGCGGC
AGTTAGCGATTGTTGTGATTATGGCTCAAATGGGCTCTTATGTTTCAGCTGAAAGCGCTCAATTGCCGATTTTTGATGCA
ATCTTTACTCGAATTGGTGCAGCTGATGACTTGGTTTCTGGACAATCAACCTTTATGATTGAAATGATGGAAGCGAACCA
TGCTATTTCTCAAGCAACAGAAAATTCACTCATTCTTTTTGATGAGTTAGGAAGAGGAACAGCCACCTATGATGGCATGG
CGCTTGCTCAAGCTATTATTGAGTATATTCACAATCGGACAGGAGCTAAGACACTTTTTGCGACTCACTATCACGAGTTG
ACAGAACTGTCAACTAGCTTGACACAACTAGAAAATGTCCATGTAGCAACCCTAGAAAAAGATGGTCAAGTAACATTTCT
TCATAAGATTGAGGTTGGACCTGCTGATAAATCTTATGGGCTTCATGTAGCAAAAATTGCAGGTTTGCCAAATGATTTGT
TGACAAGAGCGGATCAAATATTGACACGATTAGAAAGCCAAGTAAATGAGAAGCCATCTTTTGGCATCTTTAATACATTA
CCTGCGGATGCTCGTGAAAAAAATCAAGTGGCTGAGCAGATGTCTTTATTTACAGAAACAACTGAATCACCTATTTTAGA
CGAGTTGCGCCAGTTGGACATTTATAATATGACCCCAATGGAAGTGATGTTGGCTGTGGCAGAGATAAAGAAGAAACTTT
AA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (255-546)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	76.671	100	0.767
mutS	Pseudomonas stutzeri strain ATCC 17587	36.343	100	0.368