Detailed information NTG0768264

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: O2609_RS13305
• Genome accession: NZ_CP115046
• Coordinates: 2659985..2660872 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain ATCC 25923 WZlab
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2654985..2665872

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
O2609_RS13275 (O2609_13270)	-	2655004..2655096 (+)	93	WP_010956583.1	hypothetical protein	-
O2609_RS13280 (O2609_13275)	-	2655204..2655701 (-)	498	WP_001065268.1	glutathione peroxidase	-
O2609_RS13285 (O2609_13280)	-	2655711..2655971 (-)	261	WP_001791974.1	hypothetical protein	-
O2609_RS13290 (O2609_13285)	-	2656353..2656466 (-)	114	Protein_2575	hypothetical protein	-
O2609_RS13295 (O2609_13290)	-	2657125..2659125 (-)	2001	WP_000776751.1	ABC transporter permease	-
O2609_RS13300 (O2609_13295)	-	2659122..2659877 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
O2609_RS13305 (O2609_13300)	braS	2659985..2660872 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
O2609_RS13310 (O2609_13305)	braR	2660883..2661548 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
O2609_RS13315 (O2609_13310)	-	2661574..2661774 (-)	201	WP_000604730.1	hypothetical protein	-
O2609_RS13320 (O2609_13315)	-	2661972..2663396 (+)	1425	WP_000953755.1	alkaline phosphatase	-
O2609_RS13325	-	2663456..2663557 (-)	102	WP_000731976.1	SE2200 family small protein	-
O2609_RS13330 (O2609_13325)	-	2663679..2664134 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
O2609_RS13335 (O2609_13330)	-	2664379..2665140 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=768264 O2609_RS13305 WP_000143425.1 2659985..2660872(-) (braS) [Staphylococcus aureus strain ATCC 25923 WZlab]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=768264 O2609_RS13305 WP_000143425.1 2659985..2660872(-) (braS) [Staphylococcus aureus strain ATCC 25923 WZlab]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1