Detailed information NTG0767968

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: QPR37_RS03860
• Genome accession: NZ_CP126631
• Coordinates: 824754..826862 (-)
• Length: 702 a.a.
• NCBI ID: WP_063650439.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain 33-40
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 819754..831862

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QPR37_RS03845 (QPR37_03845)	-	822272..822499 (+)	228	WP_000932073.1	ferrous iron transport protein A	-
QPR37_RS03850 (QPR37_03850)	feoB	822511..824505 (+)	1995	WP_285146260.1	ferrous iron transport protein B	-
QPR37_RS03855 (QPR37_03855)	-	824518..824688 (+)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
QPR37_RS03860 (QPR37_03860)	clpE	824754..826862 (-)	2109	WP_063650439.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
QPR37_RS03865 (QPR37_03865)	-	827223..827744 (+)	522	WP_000262599.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
QPR37_RS03870 (QPR37_03870)	-	827915..829081 (-)	1167	WP_000151980.1	hydroxymethylglutaryl-CoA synthase	-
QPR37_RS03875 (QPR37_03875)	-	829336..830616 (+)	1281	WP_001191006.1	hydroxymethylglutaryl-CoA reductase, degradative	-
QPR37_RS03880 (QPR37_03880)	-	830756..831187 (-)	432	WP_000455861.1	CHAP domain-containing protein	-
QPR37_RS03885 (QPR37_03885)	-	831577..831795 (-)	219	WP_000011686.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78077.66 Da
• Isoelectric Point: 4.7115

>NTDB_id=767968 QPR37_RS03860 WP_063650439.1 824754..826862(-) (clpE) [Staphylococcus aureus strain 33-40]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSARDTVEILKGIREKFEAHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNVIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEDLGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=767968 QPR37_RS03860 WP_063650439.1 824754..826862(-) (clpE) [Staphylococcus aureus strain 33-40]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
CTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGCGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACAACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAGAGA
TACGGTTGAAATTTTAAAAGGAATTCGCGAAAAATTTGAAGCACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCTTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAATGTAATTAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAACGGTGCACGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAGGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTACAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGCCCTGAATTTCTTAACCGCTTCAATGGTATTGTGGAATTCTTACACCTAGATAAAG
AGTCACTACAAGAAATCATTAATTTATTGTTGGATGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGACTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ACGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA lid domain (AAA_lid_9) (265-363)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.745	91.595	0.437
clpC	Lactococcus lactis subsp. cremoris KW2	46.203	90.028	0.416
clpE	Streptococcus pneumoniae Rx1	47.326	87.892	0.416
clpE	Streptococcus pneumoniae D39	47.326	87.892	0.416
clpE	Streptococcus pneumoniae R6	47.326	87.892	0.416
clpE	Streptococcus pneumoniae TIGR4	47.326	87.892	0.416
clpC	Bacillus subtilis subsp. subtilis str. 168	44.037	93.162	0.41
clpC	Streptococcus thermophilus LMD-9	44.64	89.031	0.397
clpC	Streptococcus thermophilus LMG 18311	44.48	89.031	0.396
clpC	Streptococcus pneumoniae TIGR4	43.82	88.746	0.389
clpC	Streptococcus pneumoniae Rx1	43.82	88.746	0.389
clpC	Streptococcus pneumoniae D39	43.82	88.746	0.389
clpC	Streptococcus mutans UA159	43.577	87.607	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.055	88.746	0.373