Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   LpnA194_RS03135 Genome accession   NZ_CP114578
Coordinates   663193..665400 (-) Length   735 a.a.
NCBI ID   WP_027219364.1    Uniprot ID   A0A378K2I8
Organism   Legionella pneumophila strain A194     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 658193..670400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LpnA194_RS03115 (LpnA194_00622) - 658669..660597 (-) 1929 WP_011945785.1 hypothetical protein -
  LpnA194_RS03120 (LpnA194_00623) - 660723..661115 (-) 393 WP_027219365.1 hypothetical protein -
  LpnA194_RS03125 (LpnA194_00624) - 661252..661629 (+) 378 WP_011945787.1 hypothetical protein -
  LpnA194_RS03130 (LpnA194_00625) - 661830..663137 (+) 1308 WP_011945788.1 tetratricopeptide repeat protein -
  LpnA194_RS03135 (LpnA194_00626) comEC 663193..665400 (-) 2208 WP_027219364.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LpnA194_RS03140 (LpnA194_00627) pilE 665478..665927 (-) 450 WP_010946364.1 type IV pilin protein Machinery gene
  LpnA194_RS03145 (LpnA194_00628) - 665939..669448 (-) 3510 WP_027224036.1 pilus assembly protein -
  LpnA194_RS03150 (LpnA194_00629) - 669461..669973 (-) 513 WP_027219362.1 pilus assembly protein -

Sequence

Protein


Download         Length: 735 a.a.        Molecular weight: 83266.86 Da        Isoelectric Point: 9.7684

>NTDB_id=766487 LpnA194_RS03135 WP_027219364.1 663193..665400(-) (comEC) [Legionella pneumophila strain A194]
MEIFCFLIGVLYAYTYNIYLTIAIPLLFYITPRYPIVLFFIAGCGFALIHQWIVSPKGMPDTQVITQAQLEGTIASIPMQ
RPNKTQFHFAIEKINNNPAQGLIQLNWYNKPPVLRAGQRWQLSVKLKKPRNFRNPGGFNYVRYLAARHIHWTGYIRYGNN
KLISNQPPSFSWLTLREKIGDALTKLAPNTETAGIIEALTLNVTHHISSEHWNLFRRTGTVHLFGISGEHIALVSGIFFI
VIRWIWSMSYRCCLFLPAHTIASIGGLLAALPYAFLAGFEPPVQRALIGCVLYTIYAIGKQRFTPWQIWRYALFLVLCIE
PHAVFLQGFYFSFLAVACLLLTHQRWPLKNYKKTLTLQLSCLIGLMPLTLHWYSYGSINGFLANLFSIPLVSFLIVPLAL
MTMITSPLHWSWILMKPLAWLVALLLQGLTYVEQIAGINITWSITSVTMMLAMTAGLFLRVLLPVKPFKHLAILWIILPL
FPPRTAIYPGEALINILDVGQGLAVAIQTQHHVLLYDTGDSYFQGSDLGQMAIIPFFRSIGIKTIDKIVISHPDKDHKGG
LNSLEKEMQVNQLIVNDPYFYKRGSNCHSYPQWQWDGVSFRFLPIKESFTKKNNNSCILQVSNSAGRVLLTGDIEKAAEE
YLVRNYGSQLASEILVVPHHGSKTSSSYRFLLEVNPLYAIASLGFDNRFKFPHSKTLQSMKTLDITFFRTDECGMAAIKL
PASGQVHRPSCMQAN

Nucleotide


Download         Length: 2208 bp        

>NTDB_id=766487 LpnA194_RS03135 WP_027219364.1 663193..665400(-) (comEC) [Legionella pneumophila strain A194]
ATGGAAATTTTTTGCTTTTTAATAGGCGTACTTTATGCCTATACCTATAATATTTATCTAACTATTGCGATTCCTTTACT
CTTTTATATCACACCAAGATATCCAATTGTCCTGTTCTTTATCGCCGGGTGCGGCTTTGCCCTGATTCATCAGTGGATTG
TATCTCCCAAGGGCATGCCTGATACGCAAGTAATCACTCAAGCCCAGTTGGAAGGAACAATTGCTTCCATCCCCATGCAA
CGTCCTAACAAAACTCAATTCCATTTTGCAATTGAAAAAATTAATAATAACCCTGCTCAAGGCTTGATCCAATTAAACTG
GTATAACAAACCTCCTGTCTTACGAGCCGGTCAGCGATGGCAACTTTCAGTGAAACTAAAAAAACCTCGTAATTTCCGCA
ACCCAGGAGGTTTTAATTATGTACGTTACCTGGCGGCTCGTCATATCCATTGGACTGGTTATATTCGTTATGGGAATAAT
AAGCTAATTAGCAATCAACCCCCTTCTTTCAGTTGGTTAACACTGCGTGAAAAAATAGGGGATGCTTTGACAAAACTGGC
ACCGAATACAGAAACGGCAGGCATCATCGAAGCATTGACGTTAAATGTTACTCACCATATCAGTTCAGAACATTGGAATT
TGTTCCGAAGAACAGGAACGGTACATTTATTCGGGATTTCAGGGGAGCACATCGCTCTGGTCTCCGGCATTTTCTTTATA
GTGATAAGATGGATTTGGTCAATGAGCTATCGTTGCTGCTTGTTCTTACCGGCCCATACCATAGCGAGTATCGGTGGGCT
ACTGGCCGCCTTGCCCTATGCTTTTTTAGCCGGGTTTGAACCTCCTGTACAGCGTGCTTTAATTGGTTGTGTACTTTACA
CAATATACGCCATAGGAAAACAACGTTTTACACCATGGCAAATATGGAGATACGCCTTATTTTTAGTCTTGTGTATTGAA
CCCCATGCCGTATTCCTGCAAGGTTTTTATTTTTCATTTCTTGCTGTGGCCTGTCTTCTATTGACGCACCAACGTTGGCC
ACTGAAAAATTATAAAAAAACACTGACATTACAATTAAGCTGCCTCATTGGATTGATGCCCTTGACTCTCCATTGGTACT
CCTATGGTTCTATTAATGGATTCCTTGCCAATTTATTCTCCATACCTTTAGTCAGCTTTCTGATAGTACCCTTGGCTTTA
ATGACTATGATAACGAGTCCGCTTCATTGGTCCTGGATATTGATGAAACCATTGGCATGGCTTGTTGCCCTGTTACTGCA
AGGACTAACGTATGTTGAGCAAATAGCAGGGATTAATATCACCTGGTCCATCACCTCGGTAACAATGATGCTCGCTATGA
CAGCAGGTCTGTTTTTAAGGGTATTATTACCTGTCAAGCCATTCAAACACTTGGCTATCCTTTGGATTATCCTTCCCTTA
TTTCCGCCTCGTACTGCAATTTATCCAGGGGAAGCATTAATTAATATTTTGGATGTTGGGCAAGGACTGGCTGTTGCGAT
ACAAACGCAACATCATGTTTTACTCTACGATACGGGAGATTCCTATTTTCAGGGGAGTGATTTAGGGCAAATGGCGATAA
TACCCTTTTTCAGGTCAATTGGAATAAAAACAATTGACAAAATAGTAATAAGCCATCCTGATAAAGATCATAAGGGCGGA
TTAAATTCCCTTGAAAAAGAGATGCAAGTCAATCAATTAATAGTGAATGATCCCTATTTTTATAAACGTGGAAGTAATTG
TCATTCATACCCACAATGGCAATGGGATGGGGTGAGTTTTCGTTTTTTACCCATCAAGGAATCTTTCACTAAAAAAAATA
ACAATTCTTGTATCTTACAGGTAAGTAATTCAGCTGGCAGGGTTTTATTAACGGGAGATATTGAAAAAGCGGCTGAAGAG
TACCTGGTAAGAAACTACGGCAGTCAGCTGGCATCCGAGATTTTAGTTGTGCCTCATCATGGGAGTAAAACGTCTTCATC
CTATCGATTTTTGCTGGAAGTAAACCCGCTTTATGCCATTGCATCCTTAGGATTTGATAATCGTTTCAAATTTCCACATT
CTAAAACTTTGCAAAGCATGAAAACATTAGATATCACTTTTTTTAGAACAGACGAATGCGGAATGGCAGCAATCAAACTA
CCTGCATCAGGTCAAGTTCACAGACCAAGTTGTATGCAGGCTAATTGA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(498-579)

Competence protein (Competence)

(199-464)

Domain of unknown function (DUF4131) (DUF4131)

(21-158)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A378K2I8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Legionella pneumophila strain ERS1305867

99.728

100

0.997
  comEC Legionella pneumophila strain Lp02

96.866

99.864

0.967