Detailed information NTG0766466

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: LpnH3D14_RS09820
• Genome accession: NZ_CP114576
• Coordinates: 2152059..2154791 (+)
• Length: 910 a.a.
• NCBI ID: WP_014844211.1
• Uniprot ID: -
• Organism: Legionella pneumophila strain H3
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2147059..2159791

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LpnH3D14_RS09800 (LpnH3D14_01966)	gstA	2147201..2147806 (-)	606	WP_011946805.1	glutathione transferase GstA	-
LpnH3D14_RS09805 (LpnH3D14_01967)	-	2148003..2148998 (-)	996	WP_011946806.1	hypothetical protein	-
LpnH3D14_RS09810 (LpnH3D14_01968)	-	2149039..2150301 (-)	1263	WP_011946807.1	serine hydrolase domain-containing protein	-
LpnH3D14_RS09815 (LpnH3D14_01969)	gltX	2150548..2151960 (-)	1413	WP_011946808.1	glutamate--tRNA ligase	-
LpnH3D14_RS09820 (LpnH3D14_01970)	letS	2152059..2154791 (+)	2733	WP_014844211.1	two-component system sensor histidine kinase LetS	Regulator
LpnH3D14_RS09825 (LpnH3D14_01971)	-	2154889..2156133 (+)	1245	WP_011214166.1	6-phosphofructokinase	-
LpnH3D14_RS09830 (LpnH3D14_01972)	pilA2	2156130..2156543 (-)	414	WP_013101573.1	pilin	Machinery gene
LpnH3D14_RS09835 (LpnH3D14_01973)	pilA2	2156741..2157151 (-)	411	WP_014844212.1	pilin	Machinery gene
LpnH3D14_RS09840 (LpnH3D14_01974)	-	2157454..2157771 (+)	318	WP_010947633.1	BolA family protein	-
LpnH3D14_RS09845 (LpnH3D14_01975)	-	2157846..2159267 (+)	1422	WP_014844213.1	APC family permease	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 103081.51 Da
• Isoelectric Point: 7.1664

>NTDB_id=766466 LpnH3D14_RS09820 WP_014844211.1 2152059..2154791(+) (letS) [Legionella pneumophila strain H3]
MLKSIGIKYQLRITTLIPAFLVALLFAFFYNGLFGKDLKQHMSRLGEAYIRQLLPAAQYAMLRNDYRTLQGLINASTINP
EVKALAFYNADGRLIAYRGGKHSIHKPFNPPDYTGDYIESKQINPFTINFIAPITIPKFNLYSSTEFKELSTPKIFQADD
ILGWLSIDIDTQSLLIKRYQMLIVTIFITLFGLLMGLTIHYFLSKRIYMPIARLRRSMKQILSNEFETEIRVSSPGELGI
IEKGCAHLQRQYLNTVRDLNHHIEIATADLQQSLELLEEKNIELSLEKKKTEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLSIINDILDFSKIDAGKLNLDCIPLDIRGCIDEVLSLASPNAHKKGIDLIPITD
INVPKMVLGDPLRIKQIISNLVTNAVKFTDHGYVLIRTKIEQETDKDYTLLFAITDTGIGISPEDQTKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMHGRISLTSEINKGSTFSARIKVEKLVAYEIEKNQTHRFAHLKIICFDDNPLHLEAIGNG
LGFWGIEAIRVDSFNKLSRTLTKHKDCKIAFINVNQGCERQAAELIAKHEQIPFVLISKWPINDFAALGARGFLYKPISI
QKLQDLIESIANENQTEKNTNQELDTLREQLRFLHPEILIAEDNPVNKMLLTSLLNNNANITTVDDGEMAVTACEDKKFD
MILLDLHMPKLNGLEAAKMIRQKSLMNKPSPIVIITASSSDLSSIDMKKSGVDFCFQKPIDEKQLLIQILRIVDKTKHAA
IDWQLCVQKVSGNQALAEEFLAKFIEELYKNREEFIELMHQKNVKELADLAHKLHGACCFCGVPILQKRVAQLEKLARRT
TNADNLTEAFTDLIQSIDAVISEYENQYSQ

Nucleotide

• Length: 2733 bp

>NTDB_id=766466 LpnH3D14_RS09820 WP_014844211.1 2152059..2154791(+) (letS) [Legionella pneumophila strain H3]
ATGTTGAAAAGTATTGGTATTAAATATCAGCTAAGAATCACTACTCTTATTCCTGCCTTTTTAGTCGCCTTGCTTTTTGC
TTTTTTTTATAACGGCCTATTTGGTAAAGATCTAAAGCAGCATATGTCCAGACTGGGTGAAGCCTATATTAGGCAATTAC
TTCCAGCAGCCCAGTATGCCATGCTTCGCAATGATTACCGTACATTGCAGGGTTTAATCAATGCCTCAACCATTAACCCG
GAGGTAAAAGCTTTGGCATTTTATAATGCTGATGGTCGATTAATCGCTTATCGTGGGGGCAAGCATTCTATTCATAAACC
ATTCAATCCACCTGACTATACAGGTGACTACATTGAAAGTAAGCAAATTAACCCATTCACCATTAATTTTATAGCGCCGA
TTACTATCCCAAAGTTCAATTTGTACTCCAGCACAGAATTCAAAGAGCTTTCTACGCCTAAAATATTCCAGGCTGACGAT
ATATTAGGCTGGTTATCCATTGACATTGATACACAATCACTACTTATAAAACGCTATCAAATGCTCATCGTTACCATTTT
TATTACTCTATTCGGTTTACTGATGGGTTTAACAATTCATTACTTCTTGTCTAAACGAATTTACATGCCTATTGCTCGAT
TGCGTCGAAGTATGAAGCAAATTTTAAGCAATGAATTTGAAACTGAAATTCGTGTTTCAAGTCCAGGAGAATTAGGAATA
ATTGAAAAAGGTTGCGCTCATTTACAACGACAATATTTAAATACAGTTCGTGATTTGAATCACCACATTGAAATCGCCAC
AGCAGATCTGCAACAAAGTCTCGAACTTCTGGAAGAAAAAAACATCGAGCTATCACTGGAAAAGAAAAAAACTGAAGAAA
AAAGTCGACAAAAATCAGAATTTATTGCCAACATGAGTCATGAAATTCGCACCCCAATGAATGGCGTGATTGGTTTTACA
AATGTTTTATTGGAAAGCAAGCTGGACCCTTTACAACTGGACTACGTTAAAACGATCAAATCATCAGCGCAGGATTTGTT
AAGTATCATCAATGATATTCTGGATTTTTCTAAAATTGATGCGGGCAAATTAAATCTTGATTGCATCCCGCTAGACATAA
GAGGTTGCATTGATGAGGTTTTATCCCTAGCAAGCCCCAATGCACACAAAAAAGGAATCGATTTAATCCCGATTACAGAC
ATCAATGTGCCCAAAATGGTATTGGGTGACCCTTTAAGAATCAAACAAATCATCAGTAATCTGGTGACCAATGCAGTAAA
ATTTACAGATCATGGATACGTTCTTATACGCACTAAAATCGAGCAAGAAACAGATAAAGATTATACCTTGCTATTTGCCA
TTACGGATACGGGAATAGGTATTTCACCAGAGGATCAAACGAAACTGTTTACTGCCTTCAATCAGGCAGACACCAGCATC
ACACGCCGTTACGGTGGCTCAGGATTAGGCTTGGTTATATGTAAAAAACTATGTGAAGAAATGCATGGACGTATTAGTCT
AACCAGTGAAATCAACAAAGGCTCTACTTTTAGCGCACGCATTAAAGTTGAAAAACTTGTTGCTTATGAGATTGAAAAAA
ATCAAACTCATCGTTTCGCCCATTTAAAAATCATTTGCTTTGATGACAATCCCCTCCATTTGGAAGCAATAGGTAATGGC
TTGGGATTTTGGGGTATAGAGGCTATACGCGTTGACTCATTTAATAAACTTTCCCGAACATTGACAAAACATAAAGATTG
CAAAATTGCCTTTATTAACGTCAACCAAGGATGTGAGCGACAAGCTGCTGAACTCATTGCCAAACACGAGCAAATTCCTT
TTGTGTTAATTTCCAAATGGCCTATTAATGATTTTGCGGCGCTTGGTGCTCGGGGCTTTCTTTACAAACCTATCAGCATC
CAAAAACTTCAGGATCTGATTGAATCGATAGCCAATGAAAACCAAACTGAGAAAAATACGAACCAGGAACTGGATACTTT
ACGCGAACAGCTTCGTTTTCTTCATCCAGAGATACTGATTGCAGAAGACAACCCTGTCAATAAAATGCTATTAACATCCC
TATTAAATAATAATGCCAATATAACCACGGTTGACGATGGCGAAATGGCCGTTACTGCTTGTGAGGATAAAAAATTTGAC
ATGATTTTACTGGATCTGCATATGCCAAAACTTAATGGTTTGGAAGCAGCCAAAATGATACGTCAAAAATCCCTCATGAA
TAAACCCTCTCCTATCGTTATCATTACCGCCAGTAGCAGTGATCTGAGCTCCATTGATATGAAAAAATCGGGAGTTGATT
TTTGTTTTCAAAAACCTATAGATGAAAAACAATTGTTAATCCAAATTCTTCGCATCGTTGATAAAACCAAACATGCTGCC
ATTGATTGGCAATTATGCGTTCAGAAAGTTTCAGGTAATCAAGCGCTTGCTGAAGAGTTCCTCGCCAAATTCATAGAAGA
ATTATATAAGAATCGTGAAGAGTTTATTGAGTTAATGCATCAAAAAAACGTAAAGGAGCTGGCTGATTTGGCTCATAAAT
TACATGGTGCCTGTTGTTTTTGTGGTGTGCCTATTTTACAAAAGAGAGTAGCTCAATTAGAGAAGCTTGCAAGACGAACA
ACTAATGCTGATAATTTAACCGAAGCCTTTACCGATTTAATACAAAGTATTGATGCAGTGATTAGTGAATATGAAAATCA
GTATTCACAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (678-787)

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Single cache domain 4 (sCache_4) (36-180)

• Hpt domain (Hpt) (819-899)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	99.121	100	0.991