Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   O3S98_RS06195 Genome accession   NZ_CP114456
Coordinates   1283966..1284940 (+) Length   324 a.a.
NCBI ID   WP_002446534.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain SE 4.6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1278966..1289940
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O3S98_RS06160 (O3S98_06160) rpmG 1279449..1279598 (+) 150 WP_001830957.1 50S ribosomal protein L33 -
  O3S98_RS06165 (O3S98_06165) - 1279779..1280330 (+) 552 WP_060545277.1 5-formyltetrahydrofolate cyclo-ligase -
  O3S98_RS06170 (O3S98_06170) - 1280331..1281791 (+) 1461 WP_060545278.1 rhomboid family intramembrane serine protease -
  O3S98_RS06175 (O3S98_06175) - 1281775..1281975 (+) 201 WP_002446537.1 YqgQ family protein -
  O3S98_RS06180 (O3S98_06180) - 1281975..1282961 (+) 987 WP_002446536.1 ROK family glucokinase -
  O3S98_RS06185 (O3S98_06185) - 1282961..1283287 (+) 327 WP_001831234.1 MTH1187 family thiamine-binding protein -
  O3S98_RS06190 (O3S98_06190) - 1283287..1283910 (+) 624 WP_002446535.1 MBL fold metallo-hydrolase -
  O3S98_RS06195 (O3S98_06195) comGA 1283966..1284940 (+) 975 WP_002446534.1 competence type IV pilus ATPase ComGA Machinery gene
  O3S98_RS06200 (O3S98_06200) comGB 1284912..1285979 (+) 1068 WP_060545279.1 competence type IV pilus assembly protein ComGB Machinery gene
  O3S98_RS06205 (O3S98_06205) comGC 1285997..1286314 (+) 318 WP_002446532.1 competence type IV pilus major pilin ComGC Machinery gene
  O3S98_RS06210 (O3S98_06210) comGD 1286304..1286741 (+) 438 WP_060545280.1 competence type IV pilus minor pilin ComGD -
  O3S98_RS06215 (O3S98_06215) - 1286728..1287021 (+) 294 WP_020367648.1 hypothetical protein -
  O3S98_RS06220 (O3S98_06220) - 1286945..1287436 (+) 492 WP_060545281.1 competence type IV pilus minor pilin ComGF -
  O3S98_RS06225 (O3S98_06225) - 1287601..1288113 (+) 513 WP_046044250.1 shikimate kinase -
  O3S98_RS06230 (O3S98_06230) gcvT 1288331..1289422 (+) 1092 WP_060545282.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 37261.33 Da        Isoelectric Point: 8.8257

>NTDB_id=766057 O3S98_RS06195 WP_002446534.1 1283966..1284940(+) (comGA) [Staphylococcus epidermidis strain SE 4.6]
MKILFEQIINHAIKQEASDIHFIPCEEHTIIKLRIKDELTIYDTLSFPIYKKLLIYMKFQSGLDVSTQHRAQSGRYSYKM
KRLYYLRISTLPLSLGNESCVIRIVPQYFQTKRESYEFKDFKHFMKKKQGLLLFSGPTGSGKSTLMYQMVLYAHQNLNLN
VISVEDPVEQILNGITQISVNEKAGINYESSFKAILRCDPDVILIGEIRDSTVAKYVIQASLSGHLVLSTMHANDCKGAL
LRLLEMGISVQELCQAINLISNQRLITTTTNTRQLVSELMFQSQINYFFEHNHSLPKNFTKLSTHLNKMSKEGVICEEVV
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=766057 O3S98_RS06195 WP_002446534.1 1283966..1284940(+) (comGA) [Staphylococcus epidermidis strain SE 4.6]
TTGAAAATTTTATTTGAACAGATTATCAATCATGCAATTAAGCAAGAAGCAAGTGACATACACTTTATACCATGTGAGGA
ACACACTATAATTAAGCTAAGAATTAAAGATGAGCTCACAATATATGATACACTTTCATTTCCAATTTATAAAAAATTAC
TTATATACATGAAGTTTCAATCTGGGTTAGATGTATCAACACAGCATAGGGCACAAAGTGGTAGATATAGTTATAAGATG
AAGCGTTTATATTATTTAAGAATCTCTACATTACCGTTATCATTAGGCAATGAAAGTTGTGTAATTCGTATAGTACCTCA
ATACTTCCAAACTAAACGAGAATCATATGAATTTAAAGATTTTAAACACTTCATGAAAAAGAAACAAGGTCTACTTTTGT
TTAGTGGACCAACTGGCTCTGGCAAAAGTACTTTAATGTACCAAATGGTCCTTTATGCACATCAAAATTTGAATTTAAAT
GTAATATCAGTTGAAGATCCAGTAGAACAAATACTCAATGGAATCACACAAATATCAGTTAATGAAAAGGCAGGTATAAA
TTATGAAAGCTCTTTTAAAGCCATTTTAAGGTGTGATCCAGATGTAATTTTAATTGGTGAAATCAGAGATTCTACCGTAG
CTAAATACGTGATTCAAGCCAGTTTAAGTGGACATTTAGTTTTGTCGACAATGCACGCGAATGATTGCAAGGGAGCATTA
TTACGATTATTAGAAATGGGTATTTCTGTCCAAGAGTTGTGCCAGGCAATCAATTTAATTTCTAATCAAAGATTAATCAC
TACTACTACAAATACTCGTCAACTAGTATCGGAATTAATGTTTCAAAGCCAAATCAATTATTTTTTTGAACATAATCATT
CTTTACCTAAAAATTTCACAAAATTATCTACACATTTAAACAAAATGTCTAAAGAAGGTGTTATATGTGAAGAAGTTGTC
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

70.062

100

0.701
  comGA Staphylococcus aureus N315

70.062

100

0.701