Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   O3S98_RS04585 Genome accession   NZ_CP114456
Coordinates   966132..966761 (+) Length   209 a.a.
NCBI ID   WP_060545730.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain SE 4.6     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 961132..971761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O3S98_RS04555 (O3S98_04560) - 961236..961772 (+) 537 WP_002447446.1 hypothetical protein -
  O3S98_RS04560 (O3S98_04565) - 961924..962910 (-) 987 WP_060545736.1 aromatic acid exporter family protein -
  O3S98_RS04565 (O3S98_04570) map 963084..963839 (+) 756 WP_060545734.1 type I methionyl aminopeptidase -
  O3S98_RS04570 (O3S98_04575) - 963997..964383 (+) 387 WP_002495657.1 hypothetical protein -
  O3S98_RS04575 (O3S98_04580) liaF 964398..965099 (+) 702 WP_060545732.1 cell wall-active antibiotics response protein LiaF -
  O3S98_RS04580 (O3S98_04585) vraS 965096..966142 (+) 1047 WP_341465820.1 sensor histidine kinase Regulator
  O3S98_RS04585 (O3S98_04590) vraR 966132..966761 (+) 630 WP_060545730.1 two-component system response regulator VraR Regulator
  O3S98_RS04590 (O3S98_04595) - 966818..967996 (-) 1179 WP_002487362.1 YihY/virulence factor BrkB family protein -
  O3S98_RS04595 (O3S98_04600) - 968402..968686 (-) 285 WP_002447438.1 YtxH domain-containing protein -
  O3S98_RS04600 (O3S98_04605) - 968694..969158 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  O3S98_RS04605 (O3S98_04610) - 969300..969515 (+) 216 WP_001830421.1 DUF1128 domain-containing protein -
  O3S98_RS04610 (O3S98_04615) - 969517..970758 (+) 1242 WP_002458545.1 aminopeptidase -
  O3S98_RS04615 (O3S98_04620) - 970839..971369 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23624.25 Da        Isoelectric Point: 4.6429

>NTDB_id=766049 O3S98_RS04585 WP_060545730.1 966132..966761(+) (vraR) [Staphylococcus epidermidis strain SE 4.6]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAYELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=766049 O3S98_RS04585 WP_060545730.1 966132..966761(+) (vraR) [Staphylococcus epidermidis strain SE 4.6]
GTGGCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACACAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAGGAGGCTATCACTAAAGCGTATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCTACTACTGAAATAAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAAGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCTTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTACAAGATCGAACACAAGCAGTAATCTATGCGTTTCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373