Detailed information NTG0766015

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: O3T07_RS04580
• Genome accession: NZ_CP114453
• Coordinates: 965094..966140 (+)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain SE 4.7
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 960094..971140

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
O3T07_RS04555 (O3T07_04565)	-	961234..961770 (+)	537	WP_002447446.1	hypothetical protein	-
O3T07_RS04560 (O3T07_04570)	-	961922..962908 (-)	987	WP_060545736.1	aromatic acid exporter family protein	-
O3T07_RS04565 (O3T07_04575)	map	963082..963837 (+)	756	WP_060545734.1	type I methionyl aminopeptidase	-
O3T07_RS04570 (O3T07_04580)	-	963995..964381 (+)	387	WP_002495657.1	hypothetical protein	-
O3T07_RS04575 (O3T07_04585)	liaF	964396..965097 (+)	702	WP_060545732.1	cell wall-active antibiotics response protein LiaF	-
O3T07_RS04580 (O3T07_04590)	vraS	965094..966140 (+)	1047	WP_002447441.1	sensor histidine kinase	Regulator
O3T07_RS04585 (O3T07_04595)	vraR	966130..966759 (+)	630	WP_060545730.1	two-component system response regulator VraR	Regulator
O3T07_RS04590 (O3T07_04600)	-	966816..967994 (-)	1179	WP_002487362.1	YihY/virulence factor BrkB family protein	-
O3T07_RS04595 (O3T07_04605)	-	968400..968684 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
O3T07_RS04600 (O3T07_04610)	-	968692..969156 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
O3T07_RS04605 (O3T07_04615)	-	969298..969513 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
O3T07_RS04610 (O3T07_04620)	-	969515..970756 (+)	1242	WP_002458545.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=766015 O3T07_RS04580 WP_002447441.1 965094..966140(+) (vraS) [Staphylococcus epidermidis strain SE 4.7]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=766015 O3T07_RS04580 WP_002447441.1 965094..966140(+) (vraS) [Staphylococcus epidermidis strain SE 4.7]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATAGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAGCGACTTGCTAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914