Detailed information NTG0765982

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: O3S97_RS04590
• Genome accession: NZ_CP114450
• Coordinates: 965357..966403 (+)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain SE 4.8
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 960357..971403

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
O3S97_RS04565 (O3S97_04570)	-	961497..962033 (+)	537	WP_002447446.1	hypothetical protein	-
O3S97_RS04570 (O3S97_04575)	-	962185..963171 (-)	987	WP_060545736.1	aromatic acid exporter family protein	-
O3S97_RS04575 (O3S97_04580)	map	963345..964100 (+)	756	WP_060545734.1	type I methionyl aminopeptidase	-
O3S97_RS04580 (O3S97_04585)	-	964258..964644 (+)	387	WP_002495657.1	hypothetical protein	-
O3S97_RS04585 (O3S97_04590)	liaF	964659..965360 (+)	702	WP_060545732.1	cell wall-active antibiotics response protein LiaF	-
O3S97_RS04590 (O3S97_04595)	vraS	965357..966403 (+)	1047	WP_002447441.1	sensor histidine kinase	Regulator
O3S97_RS04595 (O3S97_04600)	vraR	966393..967022 (+)	630	WP_060545730.1	two-component system response regulator VraR	Regulator
O3S97_RS04600 (O3S97_04605)	-	967079..968257 (-)	1179	WP_002487362.1	YihY/virulence factor BrkB family protein	-
O3S97_RS04605 (O3S97_04610)	-	968663..968947 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
O3S97_RS04610 (O3S97_04615)	-	968955..969419 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
O3S97_RS04615 (O3S97_04620)	-	969561..969776 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
O3S97_RS04620 (O3S97_04625)	-	969778..971019 (+)	1242	WP_002458545.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=765982 O3S97_RS04590 WP_002447441.1 965357..966403(+) (vraS) [Staphylococcus epidermidis strain SE 4.8]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=765982 O3S97_RS04590 WP_002447441.1 965357..966403(+) (vraS) [Staphylococcus epidermidis strain SE 4.8]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATAGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAGCGACTTGCTAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914