Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   CC22TP_RS03010 Genome accession   NZ_AP025177
Coordinates   653390..654064 (+) Length   224 a.a.
NCBI ID   WP_001166505.1    Uniprot ID   Q2FIY0
Organism   Staphylococcus aureus strain TPS6281     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 648390..659064
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CC22TP_RS02985 (TPS6281TP_05530) - 648605..649672 (+) 1068 WP_000980142.1 membrane protein -
  CC22TP_RS02990 (TPS6281TP_05540) - 649823..650866 (+) 1044 WP_001078080.1 alpha/beta hydrolase -
  CC22TP_RS02995 (TPS6281TP_05550) - 651195..651623 (+) 429 WP_000198504.1 hypothetical protein -
  CC22TP_RS03000 (TPS6281TP_05560) - 651832..652338 (-) 507 WP_000940129.1 GNAT family N-acetyltransferase -
  CC22TP_RS03005 (TPS6281TP_05570) graX 652451..653374 (+) 924 WP_000802952.1 auxiliary protein GraX/ApsX -
  CC22TP_RS03010 (TPS6281TP_05580) braR 653390..654064 (+) 675 WP_001166505.1 response regulator transcription factor GraR/ApsR Regulator
  CC22TP_RS03015 (TPS6281TP_05590) graS 654057..655097 (+) 1041 WP_001061259.1 histidine kinase GraS/ApsS -
  CC22TP_RS03020 (TPS6281TP_05600) vraF 655244..656005 (+) 762 WP_000153733.1 ABC transporter ATP-binding protein VraF -
  CC22TP_RS03025 (TPS6281TP_05610) - 655995..657884 (+) 1890 WP_000009398.1 FtsX-like permease family protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 26078.92 Da        Isoelectric Point: 4.3968

>NTDB_id=76569 CC22TP_RS03010 WP_001166505.1 653390..654064(+) (braR) [Staphylococcus aureus strain TPS6281]
MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSR
DNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDQTIFLSKTEMIIL
EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=76569 CC22TP_RS03010 WP_001166505.1 653390..654064(+) (braR) [Staphylococcus aureus strain TPS6281]
ATGCAAATACTACTAGTAGAAGATGACAATACTTTGTTTCAAGAATTGAAAAAAGAATTAGAACAATGGGATTTTAATGT
TGCTGGTATTGAAGATTTCGGCAAAGTAATGGATACATTTGAAAGTTTTAATCCTGAAATTGTTATATTGGATGTTCAAT
TACCTAAATATGATGGGTTTTATTGGTGCAGAAAAATGAGAGAAGTTTCCAATGTGCCAATATTATTCTTATCATCTCGT
GACAACCCGATGGATCAAGTGATGAGTATGGAACTTGGCGCAGATGATTATATGCAAAAGCCTTTTTATACAAATGTATT
AATTGCTAAATTACAAGCGATTTATCGTCGTGTCTATGAGTTTACAGCTGAAGAAAAACGTACATTGACTTGGCAAGATG
CTGTCGTTGATCTATCAAAAGACAGTATACAAAAAGGTGATCAGACGATTTTCCTGTCTAAAACAGAAATGATTATTTTA
GAAATTCTTATTACCAAAAAAAATCAAATCGTTTCGAGAGATACAATTATCACTGCATTATGGGATGATGAAGCATTTGT
TAGTGATAATACGTTAACAGTAAATGTGAATCGTTTACGAAAAAAATTATCTGAAATTAGTATGGATAGTGCAATCGAAA
CAAAAGTAGGAAAAGGATATATGGCTCATGAATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(148-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2FIY0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

40.909

98.214

0.402

Multiple sequence alignment