Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   QM970_RS06475 Genome accession   NZ_CP125980
Coordinates   1242217..1242873 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   P37958
Organism   Bacillus subtilis strain ZKY03     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1237217..1247873
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QM970_RS06445 (QM970_06435) oppF 1237680..1238597 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  QM970_RS06450 (QM970_06440) yjbB 1238705..1239922 (+) 1218 WP_264379461.1 MFS transporter -
  QM970_RS06455 (QM970_06445) yjbC 1240087..1240665 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  QM970_RS06460 (QM970_06450) spx 1240846..1241241 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  QM970_RS06465 (QM970_06455) yjbE 1241284..1241940 (-) 657 WP_003232944.1 TerC family protein -
  QM970_RS06470 (QM970_06460) - 1242110..1242250 (+) 141 WP_119122854.1 hypothetical protein -
  QM970_RS06475 (QM970_06465) mecA 1242217..1242873 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  QM970_RS06480 (QM970_06470) - 1242868..1242990 (-) 123 WP_003245684.1 hypothetical protein -
  QM970_RS06485 (QM970_06475) coiA 1243034..1244185 (+) 1152 WP_046380934.1 competence protein CoiA Machinery gene
  QM970_RS06490 (QM970_06480) pepF 1244415..1246244 (+) 1830 WP_173401378.1 oligoendopeptidase F Regulator
  QM970_RS06495 (QM970_06485) - 1246282..1246449 (-) 168 WP_003244944.1 hypothetical protein -
  QM970_RS06500 (QM970_06490) spxH 1246764..1247663 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=765518 QM970_RS06475 WP_003245194.1 1242217..1242873(+) (mecA) [Bacillus subtilis strain ZKY03]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=765518 QM970_RS06475 WP_003245194.1 1242217..1242873(+) (mecA) [Bacillus subtilis strain ZKY03]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 2Y1R
  PDB 3J3R
  PDB 3J3S
  PDB 3J3T
  PDB 3J3U
  PDB 3JTP
  PDB 3PXG
  PDB 3PXI

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1