Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QLQ05_RS00585 Genome accession   NZ_CP125762
Coordinates   101988..103190 (+) Length   400 a.a.
NCBI ID   WP_009969578.1    Uniprot ID   P39668
Organism   Bacillus subtilis strain KRS015     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 96988..108190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QLQ05_RS00565 walK 97069..98904 (+) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -
  QLQ05_RS00570 walH 98894..100261 (+) 1368 WP_003242498.1 WalRK two-component regulatory system regulator WalH -
  QLQ05_RS00575 walI 100248..101090 (+) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  QLQ05_RS00580 vicX 101112..101906 (+) 795 WP_003242676.1 MBL fold metallo-hydrolase Regulator
  QLQ05_RS00585 htrA 101988..103190 (+) 1203 WP_009969578.1 serine protease HtrC Regulator
  QLQ05_RS00590 - 103210..103338 (+) 129 WP_003242634.1 hypothetical protein -
  QLQ05_RS00595 - 103455..103643 (+) 189 Protein_103 ATP-binding protein -
  QLQ05_RS00600 rocR 103625..105010 (-) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  QLQ05_RS00605 rocD 105251..106456 (+) 1206 WP_003242970.1 ornithine aminotransferase -
  QLQ05_RS00610 rocE 106679..108082 (+) 1404 WP_003242721.1 amino acid permease -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42788.56 Da        Isoelectric Point: 5.3354

>NTDB_id=763822 QLQ05_RS00585 WP_009969578.1 101988..103190(+) (htrA) [Bacillus subtilis strain KRS015]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNMSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=763822 QLQ05_RS00585 WP_009969578.1 101988..103190(+) (htrA) [Bacillus subtilis strain KRS015]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATATGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCTGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCTGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGTGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTATCGCGGCGGAAAAGAAAAATCTGTTGATATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(203-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P39668

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.577

99.25

0.433
  htrA Streptococcus gordonii str. Challis substr. CH1

41.294

100

0.415
  htrA Streptococcus mitis NCTC 12261

42.746

96.5

0.412
  htrA Streptococcus pneumoniae TIGR4

44.848

82.5

0.37
  htrA Streptococcus pneumoniae D39

44.848

82.5

0.37
  htrA Streptococcus pneumoniae Rx1

44.848

82.5

0.37
  htrA Streptococcus pneumoniae R6

44.848

82.5

0.37