Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   OHP008_RS04215 Genome accession   NZ_AP024965
Coordinates   872249..873484 (+) Length   411 a.a.
NCBI ID   WP_223887960.1    Uniprot ID   -
Organism   Helicobacter pylori strain #8     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 867249..878484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHP008_RS04195 - 867308..867722 (-) 415 Protein_823 CAAX protease -
  OHP008_RS04200 (OHP008_08410) - 867673..869595 (+) 1923 WP_223888778.1 type IA DNA topoisomerase -
  OHP008_RS08125 (OHP008_08420) - 869595..869723 (+) 129 WP_001185488.1 hypothetical protein -
  OHP008_RS04205 (OHP008_08430) - 869725..870711 (+) 987 WP_212855314.1 VirB8/TrbF family protein -
  OHP008_RS04210 (OHP008_08440) - 870711..872252 (+) 1542 WP_223887959.1 TrbG/VirB9 family P-type conjugative transfer protein -
  OHP008_RS04215 (OHP008_08450) comB10 872249..873484 (+) 1236 WP_223887960.1 DNA type IV secretion system protein ComB10 Machinery gene
  OHP008_RS04220 (OHP008_08460) - 873554..873847 (+) 294 WP_223887961.1 hypothetical protein -
  OHP008_RS04225 (OHP008_08470) - 873840..874103 (+) 264 WP_223887962.1 hypothetical protein -
  OHP008_RS04230 (OHP008_08480) - 874100..874399 (+) 300 WP_220974406.1 hypothetical protein -
  OHP008_RS04235 (OHP008_08490) - 874399..875340 (+) 942 WP_223887963.1 CpaF/VirB11 family protein -
  OHP008_RS04240 - 875337..875429 (+) 93 Protein_833 mobilization protein -
  OHP008_RS04245 (OHP008_08500) - 875409..875693 (-) 285 WP_223887964.1 hypothetical protein -
  OHP008_RS04250 (OHP008_08510) - 875804..876130 (-) 327 WP_223887965.1 hypothetical protein -
  OHP008_RS04255 (OHP008_08520) - 876210..876491 (-) 282 WP_088297872.1 YafQ family addiction module toxin -
  OHP008_RS04260 (OHP008_08530) - 876484..876798 (-) 315 WP_180528189.1 hypothetical protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 46490.51 Da        Isoelectric Point: 10.0077

>NTDB_id=76276 OHP008_RS04215 WP_223887960.1 872249..873484(+) (comB10) [Helicobacter pylori strain #8]
MKKLLLLLEHKIIKIGLIIVIVLAGFFLFYEQEIKEKAVNVSQGKFPTSSYLFQAYEGIKNKIDTINEVKPNDETKSVNE
NIEKTQKDLDDFNALVQKLPNLPKDFNKTLIKPQSPSFNYNTANEEEKTRLVILASRISSQKETQPPTSIKNSVSNTKSK
EKQEFEKEYGSSGFKNFKRKNIASSENKLLRTITADRMIPAILITPISSEIGGSKIIAQVESDIYATMGRAVLIPKGSRA
IGYYNSNNKIGEYRLEIAWNRIITPQGVNIILSDAKGADVKGYNGMIGTLHNKYWERYGIPLSLSTLSNGLLIGLTSGLT
EAMKNKRGGFNQNYFGDYMMMQMTRQTGISLNNIIAQIMRDQIRIKPIITIREGSHIFISPNTDIWFPIPKNNEVLAKFF
NEEKEQNNDTK

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=76276 OHP008_RS04215 WP_223887960.1 872249..873484(+) (comB10) [Helicobacter pylori strain #8]
ATGAAAAAACTTCTTTTACTTTTAGAGCATAAAATCATAAAAATTGGCTTAATTATTGTGATTGTATTAGCTGGTTTTTT
TCTTTTTTACGAACAAGAAATCAAAGAAAAAGCTGTTAATGTTTCTCAAGGTAAATTCCCTACTTCATCTTATTTGTTTC
AAGCTTACGAAGGCATTAAGAATAAAATAGATACTATCAATGAAGTGAAACCAAACGATGAAACTAAAAGCGTTAATGAG
AATATAGAAAAAACACAAAAAGATTTAGATGATTTTAATGCTCTAGTGCAAAAATTACCAAATTTGCCTAAGGATTTTAA
TAAAACGCTTATTAAACCACAAAGTCCATCCTTCAACTACAATACCGCTAACGAAGAAGAAAAAACCCGCCTTGTGATTT
TGGCTTCTCGTATTAGCAGTCAAAAAGAAACGCAACCTCCAACCTCTATAAAAAATAGTGTTTCTAACACAAAGTCCAAA
GAAAAACAAGAATTTGAAAAAGAATACGGCTCTAGCGGTTTTAAAAATTTTAAAAGAAAAAATATAGCGAGCAGTGAAAA
CAAACTTTTGAGAACGATTACAGCTGACAGAATGATCCCAGCCATTCTGATCACTCCTATTAGCAGTGAAATAGGGGGTA
GTAAGATAATCGCTCAAGTGGAGAGTGATATATACGCAACGATGGGTAGAGCGGTTTTAATCCCCAAAGGGAGTAGAGCC
ATAGGCTATTACAACTCTAATAACAAAATAGGAGAATACCGCTTAGAAATTGCTTGGAATAGGATCATCACGCCACAAGG
GGTCAATATCATACTAAGCGATGCTAAGGGAGCTGATGTCAAGGGTTATAATGGCATGATAGGCACACTCCATAACAAAT
ATTGGGAACGCTATGGCATTCCTTTATCTTTAAGCACCTTGTCAAATGGGCTACTCATAGGTCTTACTAGCGGTCTTACC
GAAGCGATGAAAAACAAAAGGGGTGGTTTTAACCAAAACTATTTTGGAGACTACATGATGATGCAAATGACGAGACAAAC
TGGTATCAGCCTAAATAACATTATCGCTCAAATCATGCGAGATCAAATCAGGATTAAGCCCATTATCACTATTAGAGAAG
GAAGCCATATTTTTATTAGTCCTAATACGGATATTTGGTTTCCTATCCCTAAAAACAATGAAGTCTTAGCGAAATTTTTT
AATGAAGAAAAGGAACAAAACAATGATACAAAATAG

Domains

Predicted by InterProScan.

Bacterial conjugation TrbI-like protein (TrbI)

(192-387)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

55.517

70.56

0.392