Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   OQG81_RS02750 Genome accession   NZ_CP113440
Coordinates   498177..500093 (+) Length   638 a.a.
NCBI ID   WP_265643955.1    Uniprot ID   A0AA47FD60
Organism   Streptococcus macedonicus strain E37     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 493177..505093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OQG81_RS02735 (OQG81_02735) fmt 495155..496090 (+) 936 WP_265643956.1 methionyl-tRNA formyltransferase -
  OQG81_RS02740 (OQG81_02740) rsmB 496080..497402 (+) 1323 WP_014294068.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  OQG81_RS02745 (OQG81_02745) - 497440..498177 (+) 738 WP_014294069.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  OQG81_RS02750 (OQG81_02750) pknB 498177..500093 (+) 1917 WP_265643955.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  OQG81_RS02755 (OQG81_02755) liaF 500204..500899 (+) 696 WP_014294071.1 cell wall-active antibiotics response protein LiaF -
  OQG81_RS02760 (OQG81_02760) - 500896..501921 (+) 1026 WP_014294072.1 sensor histidine kinase -
  OQG81_RS02765 (OQG81_02765) - 501905..502549 (+) 645 WP_009853571.1 response regulator transcription factor -
  OQG81_RS02770 (OQG81_02770) - 502668..504068 (+) 1401 WP_014294073.1 Cof-type HAD-IIB family hydrolase -
  OQG81_RS02775 (OQG81_02775) - 504068..504424 (+) 357 WP_014294074.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 638 a.a.        Molecular weight: 68996.14 Da        Isoelectric Point: 5.0183

>NTDB_id=762283 OQG81_RS02750 WP_265643955.1 498177..500093(+) (pknB) [Streptococcus macedonicus strain E37]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALFYNRSREPKLVFEDTENTKTLPKVTTSTSVPSTTEQLLKKQKAAKED
KAATENKATKAKTKKKKSHRMFGTLMKIFFAVVIVAIAIFTYLTLTSPSTVSVPDVAGSSLSEAKTTIKSSGLKVGTVHE
VSSDTVESGYVIKTSPTAGSSKKEGSSIDIYVSKGLSGFKIKDYTGQDYQTAVKDLVNNYGVSESQIKIEEVSTSDYDEG
VIISQTPSEGGTFKVSGDDKITFKVATESTVTMPNLTGYTYSEAIAALTALGVSSSHITAYQANPNSSTGYVQVSSPSST
ATVTAQTPYYGDTLSDNVVLYLAADEEESSQAPSSSSSESSESKESSSSSSESSESKESSSSSSSTDDSSSSTETSDE

Nucleotide


Download         Length: 1917 bp        

>NTDB_id=762283 OQG81_RS02750 WP_265643955.1 498177..500093(+) (pknB) [Streptococcus macedonicus strain E37]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTGGCAAAAGATCTCATTCTTGATAATGAAGAAGTTGCCATTAAGGTGCTTCGGACGAATTATCAGACTGATCAAATTG
CCGTAGCGCGTTTCCAACGGGAAGCGCGTGCCATGGCAGAACTGAACCATCCAAATATTGTCTCGATTCGTGATATTGGA
GAAGAAGATGGACAGCAATTCTTAGTAATGGAATATGTTGATGGCTCGGACTTAAAAAAATACATTCAAGATCATGCTCC
GCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCCTATCTGCGATGACTTTGGCGCATCAACAAGGAATTGTTC
ACCGTGATTTAAAACCACAAAATATATTATTAACCAAAGACGGAACTGTTAAAGTTACTGATTTTGGTATCGCCGTAGCC
TTTGCCGAAACAAGTTTAACGCAAACCAATTCAATGCTAGGTAGTGTGCATTATTTATCGCCTGAACAAGCACGTGGTTC
AAAAGCGACTGTTCAAAGTGATATTTACGCTATGGGGATTATGTTGTTTGAAATGTTAACAGGTCACATCCCATATGATG
GCGATTCAGCTGTTACCATTGCGCTTCAACATTTCCAAAAACCACTTCCTTCCATCATTGATGAGAATAAAAATGTGCCA
CAAGCACTAGAAAATGTTGTTATCAAGGCGACTGCAAAACGTTTAAGTGACCGTTATGCGTCAACTTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTTTTACAACCGTAGCCGTGAACCTAAACTTGTTTTTGAAGATACTGAAAATACAAAGACAC
TTCCAAAGGTAACAACATCAACATCTGTTCCTTCAACGACAGAACAACTTTTGAAGAAACAAAAAGCAGCTAAAGAAGAT
AAAGCAGCAACAGAAAACAAAGCGACTAAAGCTAAAACAAAGAAGAAAAAATCACATCGTATGTTCGGCACGTTAATGAA
AATCTTTTTTGCAGTTGTGATTGTAGCTATTGCTATCTTTACATACTTGACGTTGACCTCACCATCAACCGTGAGTGTTC
CAGATGTTGCTGGCTCTAGTTTATCAGAAGCAAAAACAACGATAAAATCATCAGGTCTTAAAGTTGGAACCGTTCATGAA
GTATCAAGCGATACCGTCGAGAGTGGTTACGTTATTAAGACAAGTCCAACTGCTGGTTCATCGAAAAAAGAAGGGTCATC
AATTGATATTTACGTATCAAAAGGCTTATCAGGATTCAAGATAAAAGACTATACAGGTCAAGATTATCAAACAGCCGTTA
AAGATTTGGTTAATAATTATGGTGTTTCAGAGTCGCAAATTAAGATTGAAGAAGTCTCAACGTCAGATTATGACGAAGGT
GTTATCATCAGTCAAACACCTAGCGAAGGTGGAACCTTTAAGGTAAGTGGTGATGATAAGATTACCTTTAAAGTAGCTAC
TGAGAGTACAGTAACAATGCCGAATTTGACAGGATATACTTATTCAGAAGCTATTGCTGCCCTGACGGCTCTAGGTGTAT
CAAGTTCACATATTACGGCTTATCAAGCCAATCCCAATTCATCTACGGGTTATGTGCAAGTAAGCTCACCATCTTCAACA
GCAACTGTCACTGCTCAGACACCATATTATGGTGATACACTAAGTGATAACGTGGTACTTTACCTAGCAGCTGATGAAGA
AGAAAGCTCACAGGCACCATCGTCATCAAGCTCAGAATCCTCTGAATCAAAAGAATCAAGTTCATCAAGCTCAGAATCCT
CTGAATCAAAAGAATCAAGTTCATCAAGCAGTAGTACAGATGACAGTAGCTCATCGACAGAAACAAGTGATGAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(511-580)

PASTA domain (PASTA)

(440-506)

PASTA domain (PASTA)

(371-434)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

68.484

92.006

0.63
  stkP/pknB Streptococcus salivarius strain HSISS4

62.421

99.687

0.622
  stkP Streptococcus pneumoniae TIGR4

58.349

83.542

0.487
  stkP Streptococcus pneumoniae D39

58.161

83.542

0.486
  stkP Streptococcus pneumoniae R6

58.161

83.542

0.486
  stkP Streptococcus pneumoniae Rx1

57.974

83.542

0.484