Detailed information NTG0762076

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: OXA87_RS09525
• Genome accession: NZ_CP113435
• Coordinates: 2114296..2117028 (+)
• Length: 910 a.a.
• NCBI ID: WP_014844211.1
• Uniprot ID: -
• Organism: Legionella pneumophila strain PATHC025
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2109296..2122028

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OXA87_RS09505 (OXA87_09505)	gstA	2109438..2110043 (-)	606	WP_011946805.1	glutathione transferase GstA	-
OXA87_RS09510 (OXA87_09510)	-	2110240..2111235 (-)	996	WP_013101570.1	hypothetical protein	-
OXA87_RS09515 (OXA87_09515)	-	2111276..2112538 (-)	1263	WP_013101571.1	serine hydrolase domain-containing protein	-
OXA87_RS09520 (OXA87_09520)	gltX	2112785..2114197 (-)	1413	WP_011946808.1	glutamate--tRNA ligase	-
OXA87_RS09525 (OXA87_09525)	letS	2114296..2117028 (+)	2733	WP_014844211.1	two-component system sensor histidine kinase LetS	Regulator
OXA87_RS09530 (OXA87_09530)	-	2117126..2118370 (+)	1245	WP_011214166.1	6-phosphofructokinase	-
OXA87_RS09535 (OXA87_09535)	pilA2	2118367..2118780 (-)	414	WP_013101573.1	pilin	Machinery gene
OXA87_RS09540 (OXA87_09540)	pilA2	2118978..2119388 (-)	411	WP_014844212.1	pilin	Machinery gene
OXA87_RS09545 (OXA87_09545)	-	2119691..2120008 (+)	318	WP_010947633.1	BolA family protein	-
OXA87_RS09550 (OXA87_09550)	-	2120083..2121504 (+)	1422	WP_014844213.1	APC family permease	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 103081.51 Da
• Isoelectric Point: 7.1664

>NTDB_id=762076 OXA87_RS09525 WP_014844211.1 2114296..2117028(+) (letS) [Legionella pneumophila strain PATHC025]
MLKSIGIKYQLRITTLIPAFLVALLFAFFYNGLFGKDLKQHMSRLGEAYIRQLLPAAQYAMLRNDYRTLQGLINASTINP
EVKALAFYNADGRLIAYRGGKHSIHKPFNPPDYTGDYIESKQINPFTINFIAPITIPKFNLYSSTEFKELSTPKIFQADD
ILGWLSIDIDTQSLLIKRYQMLIVTIFITLFGLLMGLTIHYFLSKRIYMPIARLRRSMKQILSNEFETEIRVSSPGELGI
IEKGCAHLQRQYLNTVRDLNHHIEIATADLQQSLELLEEKNIELSLEKKKTEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLSIINDILDFSKIDAGKLNLDCIPLDIRGCIDEVLSLASPNAHKKGIDLIPITD
INVPKMVLGDPLRIKQIISNLVTNAVKFTDHGYVLIRTKIEQETDKDYTLLFAITDTGIGISPEDQTKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMHGRISLTSEINKGSTFSARIKVEKLVAYEIEKNQTHRFAHLKIICFDDNPLHLEAIGNG
LGFWGIEAIRVDSFNKLSRTLTKHKDCKIAFINVNQGCERQAAELIAKHEQIPFVLISKWPINDFAALGARGFLYKPISI
QKLQDLIESIANENQTEKNTNQELDTLREQLRFLHPEILIAEDNPVNKMLLTSLLNNNANITTVDDGEMAVTACEDKKFD
MILLDLHMPKLNGLEAAKMIRQKSLMNKPSPIVIITASSSDLSSIDMKKSGVDFCFQKPIDEKQLLIQILRIVDKTKHAA
IDWQLCVQKVSGNQALAEEFLAKFIEELYKNREEFIELMHQKNVKELADLAHKLHGACCFCGVPILQKRVAQLEKLARRT
TNADNLTEAFTDLIQSIDAVISEYENQYSQ

Nucleotide

• Length: 2733 bp

>NTDB_id=762076 OXA87_RS09525 WP_014844211.1 2114296..2117028(+) (letS) [Legionella pneumophila strain PATHC025]
ATGTTGAAAAGTATTGGTATTAAATATCAGCTAAGAATCACTACTCTTATTCCTGCCTTTTTAGTCGCCTTGCTTTTTGC
TTTTTTTTATAACGGCCTATTTGGTAAAGATCTAAAGCAGCATATGTCCAGACTGGGTGAAGCCTATATTAGGCAATTAC
TTCCAGCAGCCCAGTATGCCATGCTTCGCAATGATTACCGTACATTGCAGGGTTTAATCAATGCCTCAACCATTAACCCG
GAGGTAAAAGCTTTGGCATTTTATAATGCTGATGGTCGATTAATCGCTTATCGTGGGGGCAAGCATTCTATTCATAAACC
ATTCAATCCACCTGACTATACAGGTGACTACATTGAAAGTAAGCAAATTAACCCATTCACCATTAATTTTATAGCGCCGA
TTACTATCCCAAAGTTCAATTTGTACTCCAGCACAGAATTCAAAGAGCTTTCTACGCCTAAAATATTCCAGGCTGACGAT
ATATTAGGCTGGTTATCCATTGACATTGATACACAATCACTACTTATAAAACGCTATCAAATGCTCATCGTTACCATTTT
TATTACTCTATTCGGTTTACTGATGGGTTTAACAATTCATTACTTCTTGTCTAAACGAATTTACATGCCTATTGCTCGAT
TGCGTCGAAGTATGAAGCAAATTTTAAGCAATGAATTTGAAACTGAAATTCGTGTTTCAAGTCCAGGAGAATTAGGAATA
ATTGAAAAAGGTTGCGCTCATTTACAACGACAATATTTAAATACAGTTCGTGATTTGAATCACCACATTGAAATCGCCAC
AGCAGATCTGCAACAAAGTCTCGAACTTCTGGAAGAAAAAAACATCGAGCTATCACTGGAAAAGAAAAAAACTGAAGAAA
AAAGTCGACAAAAATCAGAATTTATTGCCAACATGAGTCATGAAATTCGCACCCCAATGAATGGCGTGATTGGTTTTACA
AATGTTTTATTGGAAAGCAAGCTGGACCCTTTACAACTGGACTACGTTAAAACGATCAAATCATCAGCGCAGGATTTGTT
AAGTATCATCAATGATATTCTGGATTTTTCTAAAATTGATGCGGGCAAATTAAATCTTGATTGCATCCCGCTAGACATAA
GAGGTTGCATTGATGAGGTTTTATCCCTAGCAAGCCCCAATGCACACAAAAAAGGAATCGATTTAATCCCGATTACAGAC
ATCAATGTGCCCAAAATGGTATTGGGTGACCCTTTAAGAATCAAACAAATCATCAGTAATCTGGTGACCAATGCAGTAAA
ATTTACAGATCATGGATACGTTCTTATACGCACTAAAATCGAGCAAGAAACAGATAAAGATTATACCTTGCTATTTGCCA
TTACGGATACGGGAATAGGTATTTCACCAGAGGATCAAACGAAACTGTTTACTGCCTTCAATCAGGCAGACACCAGCATC
ACACGCCGTTACGGTGGCTCAGGATTAGGCTTGGTTATATGTAAAAAACTATGTGAAGAAATGCATGGACGTATTAGTCT
AACCAGTGAAATCAACAAAGGCTCTACTTTTAGCGCACGCATTAAAGTTGAAAAACTTGTTGCTTATGAGATTGAAAAAA
ATCAAACTCATCGTTTCGCCCATTTAAAAATCATTTGCTTTGATGACAATCCCCTCCATTTGGAAGCAATAGGTAATGGC
TTGGGATTTTGGGGTATAGAGGCTATACGCGTTGACTCATTTAATAAACTTTCCCGAACATTGACAAAACATAAAGATTG
CAAAATTGCCTTTATTAACGTCAACCAAGGATGTGAGCGACAAGCTGCTGAACTCATTGCCAAACACGAGCAAATTCCTT
TTGTGTTAATTTCCAAATGGCCTATTAATGATTTTGCGGCGCTTGGTGCTCGGGGCTTTCTTTACAAACCTATCAGCATC
CAAAAACTTCAGGATCTGATTGAATCGATAGCCAATGAAAACCAAACTGAGAAAAATACGAACCAGGAACTGGATACTTT
ACGCGAACAGCTTCGTTTTCTTCATCCAGAGATACTGATTGCAGAAGACAACCCTGTCAATAAAATGCTATTAACATCCC
TATTAAATAATAATGCCAATATAACCACGGTTGACGATGGCGAAATGGCCGTTACTGCTTGTGAGGATAAAAAATTTGAC
ATGATTTTACTGGATCTGCATATGCCAAAACTTAATGGTTTGGAAGCAGCCAAAATGATACGTCAAAAATCCCTCATGAA
TAAACCCTCTCCTATCGTTATCATTACCGCCAGTAGCAGTGATCTGAGCTCCATTGATATGAAAAAATCGGGAGTTGATT
TTTGTTTTCAAAAACCTATAGATGAAAAACAATTGTTAATCCAAATTCTTCGCATCGTTGATAAAACCAAACATGCTGCC
ATTGATTGGCAATTATGCGTTCAGAAAGTTTCAGGTAATCAAGCGCTTGCTGAAGAGTTCCTCGCCAAATTCATAGAAGA
ATTATATAAGAATCGTGAAGAGTTTATTGAGTTAATGCATCAAAAAAACGTAAAGGAGCTGGCTGATTTGGCTCATAAAT
TACATGGTGCCTGTTGTTTTTGTGGTGTGCCTATTTTACAAAAGAGAGTAGCTCAATTAGAGAAGCTTGCAAGACGAACA
ACTAATGCTGATAATTTAACCGAAGCCTTTACCGATTTAATACAAAGTATTGATGCAGTGATTAGTGAATATGAAAATCA
GTATTCACAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (678-787)

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Single cache domain 4 (sCache_4) (36-180)

• Hpt domain (Hpt) (819-899)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	99.121	100	0.991