Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   G6L16_RS01870 Genome accession   NZ_CP124963
Coordinates   378591..380411 (-) Length   606 a.a.
NCBI ID   WP_174002316.1    Uniprot ID   -
Organism   Agrobacterium tumefaciens strain AF1/95     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 373591..385411
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G6L16_RS01845 (G6L16_001845) - 374357..374596 (+) 240 WP_019564234.1 DUF4170 domain-containing protein -
  G6L16_RS01850 (G6L16_001850) waaA 374812..376134 (+) 1323 WP_174001443.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  G6L16_RS01855 (G6L16_001855) - 376128..376865 (+) 738 WP_174001444.1 HAD family hydrolase -
  G6L16_RS01860 (G6L16_001860) lpxK 377030..378076 (+) 1047 WP_174001445.1 tetraacyldisaccharide 4'-kinase -
  G6L16_RS01865 (G6L16_001865) - 378220..378441 (-) 222 WP_003519053.1 DUF2093 domain-containing protein -
  G6L16_RS01870 (G6L16_001870) hexB 378591..380411 (-) 1821 WP_174002316.1 DNA mismatch repair endonuclease MutL Machinery gene
  G6L16_RS01875 (G6L16_001875) - 380818..382437 (+) 1620 WP_174002317.1 response regulator -
  G6L16_RS01880 (G6L16_001880) - 382580..383932 (+) 1353 WP_003519050.1 putative bifunctional diguanylate cyclase/phosphodiesterase -
  G6L16_RS01885 (G6L16_001885) - 384027..384914 (-) 888 WP_174001446.1 SMP-30/gluconolactonase/LRE family protein -

Sequence

Protein


Download         Length: 606 a.a.        Molecular weight: 65145.86 Da        Isoelectric Point: 6.4000

>NTDB_id=761705 G6L16_RS01870 WP_174002316.1 378591..380411(-) (hexB) [Agrobacterium tumefaciens strain AF1/95]
MAIKQLSETLINQIAAGEVIERPSSATKELVENAIDAGATRIEIATAGGGKGLVRITDNGSGMSPADLELAVRRHCTSKI
STTLDDIRTLGFRGEALPSIGSVAKLSITSRQHGAEQGSVISVTGGKVSEVRPAAANAGTIVEVRDLFFATPARLKFLKT
ERAEAAAITEVVKRMAIAFPHIRFVLSGTDRSTLEIPSTGDDHLARMAQILGAEFKDNAIEIDAGREDVTLSGFAGVPTF
NRGNSAHQYVFVNGRPVQDKLLLSAIRGAYAETVPHGRYPVAVLSLTLDPAFVDVNVHPAKSDVRFRDPGLVRGLIVGAI
RQALTRDGDRAATTGASQMMNAFRPGYSPSNLRPSAAATWSAAASPSRPLAVSGNMQFAEAVQSRFSDITMPTARAEPRE
VYEASASPSLEPSQYPLGAARAQLHQNYIVAQTEDGLVIVDQHAAHERLVFEEMRNALHSRRPPSQVLLIPEIIDLPEED
CDRLMDHATGFDALGLVIERFGPGAVAVRETPAMLGEVNVQGLVRQLADEIAEWDAASTLANKLEYVAATMACHGSVRSG
RRMRPEEMNALLRQMENTPGSGQCNHGRPTYIELKLSDIERLFGRS

Nucleotide


Download         Length: 1821 bp        

>NTDB_id=761705 G6L16_RS01870 WP_174002316.1 378591..380411(-) (hexB) [Agrobacterium tumefaciens strain AF1/95]
ATGGCCATCAAGCAGCTTTCAGAAACCCTCATCAACCAGATCGCCGCCGGCGAGGTCATCGAAAGACCCTCCAGCGCCAC
GAAGGAGCTGGTGGAAAACGCCATCGACGCGGGCGCAACGCGCATCGAAATCGCCACGGCAGGCGGCGGCAAGGGACTGG
TGCGCATCACCGATAACGGCTCTGGCATGTCGCCTGCCGATCTGGAGCTTGCGGTCCGGCGCCATTGCACCTCGAAAATA
TCCACCACGCTTGACGATATCCGCACGCTCGGCTTTCGCGGCGAGGCTCTGCCCTCCATCGGCTCGGTTGCCAAGCTTTC
CATCACCAGCCGGCAACACGGCGCAGAACAGGGTTCGGTGATCTCCGTCACCGGCGGCAAGGTCTCCGAGGTCCGGCCTG
CCGCCGCCAATGCCGGCACCATCGTCGAGGTGCGCGACCTGTTTTTCGCGACGCCCGCACGGCTGAAATTCCTGAAGACG
GAGCGGGCGGAGGCAGCCGCCATTACCGAAGTCGTCAAGCGGATGGCGATTGCCTTTCCGCATATCCGCTTCGTGCTGTC
AGGCACCGACCGTTCCACGCTTGAAATCCCCTCCACCGGCGACGATCACCTTGCTCGCATGGCGCAGATTCTCGGTGCCG
AGTTCAAGGACAACGCCATCGAAATCGATGCCGGGCGCGAGGATGTGACGCTCTCCGGTTTTGCCGGCGTGCCGACCTTC
AACCGCGGCAACTCGGCGCATCAATATGTCTTCGTCAACGGTCGCCCGGTGCAGGACAAATTGCTGTTGTCCGCCATTCG
CGGCGCCTATGCCGAAACCGTGCCGCACGGGCGATATCCGGTCGCGGTGCTGTCCCTGACGCTCGATCCCGCCTTTGTGG
ACGTGAACGTGCATCCGGCGAAATCAGATGTGCGCTTCCGCGATCCCGGCCTTGTTCGCGGGCTGATCGTCGGTGCAATC
CGCCAGGCGCTGACCCGCGACGGCGACAGGGCGGCGACGACTGGTGCCAGCCAGATGATGAACGCCTTTCGCCCCGGCTA
CAGCCCGTCCAATCTCCGACCGTCTGCCGCTGCGACATGGTCCGCCGCGGCCTCTCCGTCCCGACCGCTTGCCGTTTCCG
GGAACATGCAATTTGCCGAGGCCGTGCAATCGCGCTTTTCCGACATCACCATGCCGACCGCGCGGGCGGAACCCCGCGAG
GTTTACGAGGCCTCCGCGAGCCCATCGCTCGAACCGTCACAATATCCGCTCGGCGCCGCGCGGGCGCAGCTGCACCAGAA
CTACATCGTCGCTCAGACGGAAGACGGCCTCGTCATCGTCGATCAGCATGCGGCGCATGAACGGCTGGTGTTTGAGGAAA
TGCGCAATGCGCTGCATTCCAGACGCCCGCCTTCACAGGTGCTGCTCATTCCTGAGATCATCGACCTTCCCGAAGAGGAT
TGCGACCGGCTGATGGACCATGCGACTGGTTTCGATGCGCTGGGGCTGGTCATCGAGCGTTTCGGACCGGGGGCGGTCGC
GGTTCGCGAAACGCCGGCGATGCTTGGCGAGGTCAACGTGCAGGGGTTGGTGCGACAGCTTGCCGACGAGATCGCCGAAT
GGGACGCCGCCTCCACGCTTGCCAACAAGCTGGAATATGTTGCCGCCACCATGGCTTGCCACGGCTCGGTGCGTTCAGGG
CGGCGCATGCGGCCGGAGGAGATGAACGCGCTTTTACGGCAGATGGAAAACACGCCGGGTTCAGGACAGTGCAATCATGG
TCGTCCGACCTATATCGAGCTGAAACTTTCCGATATAGAACGTCTCTTCGGCCGAAGCTGA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(24-122)

MutL C terminal dimerisation domain (MutL_C)

(416-562)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(208-324)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

34.317

100

0.365