Detailed information NTG0761542

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: QJ053_RS13150
• Genome accession: NZ_CP124853
• Coordinates: 2612935..2615040 (+)
• Length: 701 a.a.
• NCBI ID: WP_410530359.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain ED83
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2607935..2620040

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QJ053_RS13125 (QJ053_13125)	-	2608072..2608206 (-)	135	WP_001789912.1	hypothetical protein	-
QJ053_RS13130 (QJ053_13130)	-	2608300..2608557 (-)	258	WP_000402605.1	hypothetical protein	-
QJ053_RS13135 (QJ053_13135)	-	2609137..2610414 (-)	1278	WP_410530357.1	hydroxymethylglutaryl-CoA reductase, degradative	-
QJ053_RS13140 (QJ053_13140)	-	2610669..2611835 (+)	1167	WP_000172190.1	hydroxymethylglutaryl-CoA synthase	-
QJ053_RS13145 (QJ053_13145)	-	2612005..2612526 (-)	522	WP_410530358.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
QJ053_RS13150 (QJ053_13150)	clpE	2612935..2615040 (+)	2106	WP_410530359.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
QJ053_RS13155 (QJ053_13155)	-	2615110..2615280 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
QJ053_RS13160 (QJ053_13160)	feoB	2615293..2617287 (-)	1995	WP_000432892.1	ferrous iron transport protein B	-
QJ053_RS13165 (QJ053_13165)	-	2617299..2617526 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77905.49 Da
• Isoelectric Point: 4.7072

>NTDB_id=761542 QJ053_RS13150 WP_410530359.1 2612935..2615040(+) (clpE) [Staphylococcus aureus strain ED83]
MNNGFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISV
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELEHDKRKAVSAEEYKKADDIQKEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDTEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Nucleotide

• Length: 2106 bp

>NTDB_id=761542 QJ053_RS13150 WP_410530359.1 2612935..2615040(+) (clpE) [Staphylococcus aureus strain ED83]
ATGAATAACGGTTTTTTCAATAGCGACTTTGATTCAATTTTTCGAAGAATGATGAAAGATATGCAAGGTTCAAATCAAGT
CGGAAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTTTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGAAATGTACCAGCAGCAATCAAAGACAAAGAAATTATTTCTGTA
GACATTTCATCATTAGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATTCACCAAATCATCGGTTCCGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTGCTTGTTAATGAACCAAGCGCTAAAGA
TACTGTTGAAATTTTAAAAGGAATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAAAGAAATTAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGGTTTGATGACGGCAACCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTGGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAGGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACACTGAAGAAAAAGATATTAT
GCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTGTTATTAGACGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATGGACGTT
TCACAAGATGCGAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGAATTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATA
ACGAATTAGTCGTAAAAGGTAAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA lid domain (AAA_lid_9) (264-363)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.916	92.154	0.451
clpE	Streptococcus pneumoniae Rx1	47.974	88.017	0.422
clpE	Streptococcus pneumoniae D39	47.974	88.017	0.422
clpE	Streptococcus pneumoniae R6	47.974	88.017	0.422
clpE	Streptococcus pneumoniae TIGR4	47.896	88.16	0.422
clpC	Lactococcus lactis subsp. cremoris KW2	46.815	89.586	0.419
clpC	Bacillus subtilis subsp. subtilis str. 168	44.495	93.295	0.415
clpC	Streptococcus thermophilus LMD-9	44.96	89.158	0.401
clpC	Streptococcus thermophilus LMG 18311	44.64	89.158	0.398
clpC	Streptococcus pneumoniae Rx1	43.52	89.158	0.388
clpC	Streptococcus pneumoniae D39	43.52	89.158	0.388
clpC	Streptococcus pneumoniae TIGR4	43.689	88.16	0.385
clpC	Streptococcus mutans UA159	43.902	87.732	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.536	88.873	0.378