Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   OSZ57_RS08420 Genome accession   NZ_CP113231
Coordinates   1654124..1654840 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain BIAI 158     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1649124..1659840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OSZ57_RS08390 (OSZ57_08390) - 1649339..1649965 (+) 627 WP_000522375.1 nitroreductase family protein -
  OSZ57_RS08395 (OSZ57_08395) - 1650326..1651111 (+) 786 WP_000867944.1 carbon-nitrogen family hydrolase -
  OSZ57_RS13915 hld 1651712..1651792 (-) 81 WP_000046022.1 delta-hemolysin -
  OSZ57_RS08405 (OSZ57_08405) agrB 1652082..1652651 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  OSZ57_RS08410 (OSZ57_08410) agrD 1652648..1652788 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  OSZ57_RS08415 (OSZ57_08415) agrC 1652813..1654105 (+) 1293 WP_199916917.1 quorum-sensing sensor histidine kinase AgrC -
  OSZ57_RS08420 (OSZ57_08420) agrA 1654124..1654840 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  OSZ57_RS08425 (OSZ57_08425) - 1654912..1655019 (+) 108 WP_031785433.1 hypothetical protein -
  OSZ57_RS08430 (OSZ57_08430) - 1655209..1656168 (-) 960 WP_001253295.1 carbohydrate kinase family protein -
  OSZ57_RS08435 (OSZ57_08435) - 1656165..1657649 (-) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  OSZ57_RS08440 (OSZ57_08440) - 1657798..1658748 (-) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=761018 OSZ57_RS08420 WP_000688492.1 1654124..1654840(+) (agrA) [Staphylococcus aureus strain BIAI 158]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=761018 OSZ57_RS08420 WP_000688492.1 1654124..1654840(+) (agrA) [Staphylococcus aureus strain BIAI 158]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1