Detailed information NTG0761016

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OSZ57_RS07710
• Genome accession: NZ_CP113231
• Coordinates: 1538063..1539106 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BIAI 158
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1533063..1544106

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OSZ57_RS07680 (OSZ57_07680)	-	1533484..1534731 (-)	1248	WP_000656302.1	aminopeptidase	-
OSZ57_RS07685 (OSZ57_07685)	-	1534743..1534943 (-)	201	WP_000180459.1	DUF1128 family protein	-
OSZ57_RS07690 (OSZ57_07690)	-	1535090..1535554 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
OSZ57_RS07695 (OSZ57_07695)	-	1535561..1535836 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
OSZ57_RS07700 (OSZ57_07700)	-	1536114..1537331 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
OSZ57_RS07705 (OSZ57_07705)	vraR	1537444..1538073 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
OSZ57_RS07710 (OSZ57_07710)	vraS	1538063..1539106 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OSZ57_RS07715 (OSZ57_07715)	liaF	1539103..1539804 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
OSZ57_RS07720 (OSZ57_07720)	-	1539819..1540205 (-)	387	WP_001110184.1	hypothetical protein	-
OSZ57_RS07725 (OSZ57_07725)	map	1540422..1541180 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
OSZ57_RS07730 (OSZ57_07730)	-	1541711..1542697 (+)	987	WP_000999713.1	FUSC family protein	-
OSZ57_RS07735 (OSZ57_07735)	-	1542875..1543288 (-)	414	WP_001622129.1	hypothetical protein	-
OSZ57_RS07740 (OSZ57_07740)	-	1543317..1543426 (-)	110	Protein_1482	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=761016 OSZ57_RS07710 WP_001017131.1 1538063..1539106(-) (vraS) [Staphylococcus aureus strain BIAI 158]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=761016 OSZ57_RS07710 WP_001017131.1 1538063..1539106(-) (vraS) [Staphylococcus aureus strain BIAI 158]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1