Detailed information NTG0760234

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OSZ56_RS13650
• Genome accession: NZ_CP113105
• Coordinates: 2767050..2768093 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BIAI 117
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2762050..2773093

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OSZ56_RS13620 (OSZ56_13620)	-	2762493..2762603 (+)	111	WP_001790257.1	hypothetical protein	-
OSZ56_RS13625 (OSZ56_13625)	-	2762632..2763045 (+)	414	WP_001643743.1	hypothetical protein	-
OSZ56_RS13630 (OSZ56_13630)	-	2763234..2764220 (-)	987	WP_001014423.1	FUSC family protein	-
OSZ56_RS13635 (OSZ56_13635)	map	2764976..2765734 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
OSZ56_RS13640 (OSZ56_13640)	-	2765951..2766337 (+)	387	WP_001110178.1	hypothetical protein	-
OSZ56_RS13645 (OSZ56_13645)	liaF	2766352..2767053 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
OSZ56_RS13650 (OSZ56_13650)	vraS	2767050..2768093 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OSZ56_RS13655 (OSZ56_13655)	vraR	2768083..2768712 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
OSZ56_RS13660 (OSZ56_13660)	-	2768825..2770042 (-)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
OSZ56_RS13665 (OSZ56_13665)	-	2770320..2770595 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
OSZ56_RS13670 (OSZ56_13670)	-	2770602..2771066 (-)	465	WP_061843272.1	low molecular weight protein-tyrosine-phosphatase	-
OSZ56_RS13675 (OSZ56_13675)	-	2771213..2771413 (+)	201	WP_000180460.1	DUF1128 family protein	-
OSZ56_RS13680 (OSZ56_13680)	-	2771416..2772672 (+)	1257	WP_267810369.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=760234 OSZ56_RS13650 WP_001017131.1 2767050..2768093(+) (vraS) [Staphylococcus aureus strain BIAI 117]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=760234 OSZ56_RS13650 WP_001017131.1 2767050..2768093(+) (vraS) [Staphylococcus aureus strain BIAI 117]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1