Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   OSZ56_RS12775 Genome accession   NZ_CP113105
Coordinates   2625863..2626579 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain BIAI 117     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2620863..2631579
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OSZ56_RS12760 (OSZ56_12760) - 2621960..2622910 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  OSZ56_RS12765 (OSZ56_12765) - 2623059..2624543 (+) 1485 WP_267810550.1 glycoside hydrolase family 32 protein -
  OSZ56_RS12770 (OSZ56_12770) - 2624540..2625499 (+) 960 WP_001253292.1 carbohydrate kinase family protein -
  OSZ56_RS12775 (OSZ56_12775) agrA 2625863..2626579 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  OSZ56_RS12780 (OSZ56_12780) agrC 2626598..2627890 (-) 1293 WP_209175474.1 quorum-sensing sensor histidine kinase AgrC -
  OSZ56_RS12785 (OSZ56_12785) agrD 2627915..2628055 (-) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  OSZ56_RS12790 (OSZ56_12790) - 2628059..2628622 (-) 564 WP_001105709.1 accessory gene regulator AgrB -
  OSZ56_RS14155 (OSZ56_12795) hld 2628912..2628992 (+) 81 WP_000046022.1 delta-hemolysin -
  OSZ56_RS12800 (OSZ56_12800) - 2629687..2629857 (-) 171 Protein_2477 carbon-nitrogen family hydrolase -
  OSZ56_RS12805 (OSZ56_12805) - 2630218..2630844 (-) 627 WP_000522388.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=760232 OSZ56_RS12775 WP_000688492.1 2625863..2626579(-) (agrA) [Staphylococcus aureus strain BIAI 117]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=760232 OSZ56_RS12775 WP_000688492.1 2625863..2626579(-) (agrA) [Staphylococcus aureus strain BIAI 117]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCGACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1