Detailed information NTG0759610

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OS084_RS00610
• Genome accession: NZ_CP113052
• Coordinates: 89762..90805 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Fizz
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 84762..95805

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OS084_RS00580	-	85180..86436 (-)	1257	WP_001795438.1	aminopeptidase	-
OS084_RS00585	-	86439..86639 (-)	201	WP_000180461.1	DUF1128 family protein	-
OS084_RS00590	-	86786..87250 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
OS084_RS00595	-	87257..87532 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
OS084_RS00600	-	87810..89027 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
OS084_RS00605	vraR	89143..89772 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
OS084_RS00610	vraS	89762..90805 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OS084_RS00615	liaF	90802..91503 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
OS084_RS00620	-	91518..91904 (-)	387	WP_001110179.1	hypothetical protein	-
OS084_RS00625	map	92121..92879 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
OS084_RS00630	-	93407..94393 (+)	987	WP_000999713.1	FUSC family protein	-
OS084_RS00635	-	94883..95296 (-)	414	WP_001549145.1	hypothetical protein	-
OS084_RS00640	-	95325..95435 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=759610 OS084_RS00610 WP_001017131.1 89762..90805(-) (vraS) [Staphylococcus aureus strain Fizz]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=759610 OS084_RS00610 WP_001017131.1 89762..90805(-) (vraS) [Staphylococcus aureus strain Fizz]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1