Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   OS089_RS13640 Genome accession   NZ_CP113049
Coordinates   2754627..2755343 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain Ahri     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2749627..2760343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS089_RS13620 - 2750721..2751671 (+) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -
  OS089_RS13625 - 2751820..2753304 (+) 1485 WP_000141422.1 sucrose-6-phosphate hydrolase -
  OS089_RS13630 - 2753301..2754260 (+) 960 WP_267813957.1 carbohydrate kinase family protein -
  OS089_RS13635 - 2754448..2754555 (-) 108 WP_031844951.1 hypothetical protein -
  OS089_RS13640 agrA 2754627..2755343 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  OS089_RS13645 agrC 2755362..2756654 (-) 1293 WP_267813958.1 quorum-sensing sensor histidine kinase AgrC -
  OS089_RS13650 agrD 2756679..2756819 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  OS089_RS13655 agrB 2756816..2757385 (-) 570 WP_001105712.1 accessory gene regulator AgrB -
  OS089_RS13660 hld 2757675..2757755 (+) 81 WP_000046023.1 delta-hemolysin -
  OS089_RS13665 - 2758354..2759139 (-) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  OS089_RS13670 - 2759500..2760126 (-) 627 WP_267813959.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=759560 OS089_RS13640 WP_000688492.1 2754627..2755343(-) (agrA) [Staphylococcus aureus strain Ahri]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=759560 OS089_RS13640 WP_000688492.1 2754627..2755343(-) (agrA) [Staphylococcus aureus strain Ahri]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1