Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   OS087_RS01950 Genome accession   NZ_CP113047
Coordinates   339660..340376 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain Sett     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 334660..345376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS087_RS01920 - 334876..335502 (+) 627 WP_000522384.1 nitroreductase family protein -
  OS087_RS01925 - 335863..336648 (+) 786 WP_000867939.1 carbon-nitrogen family hydrolase -
  OS087_RS13915 hld 337248..337328 (-) 81 WP_000046022.1 delta-hemolysin -
  OS087_RS01935 agrB 337618..338187 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  OS087_RS01940 agrD 338184..338324 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  OS087_RS01945 agrC 338349..339641 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  OS087_RS01950 agrA 339660..340376 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  OS087_RS01955 - 340448..340557 (+) 110 Protein_353 hypothetical protein -
  OS087_RS01960 - 340745..341704 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  OS087_RS01965 - 341701..343185 (-) 1485 WP_000141435.1 sucrose-6-phosphate hydrolase -
  OS087_RS01970 - 343334..344284 (-) 951 WP_000790326.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=759485 OS087_RS01950 WP_000688498.1 339660..340376(+) (agrA) [Staphylococcus aureus strain Sett]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=759485 OS087_RS01950 WP_000688498.1 339660..340376(+) (agrA) [Staphylococcus aureus strain Sett]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996