Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   OS086_RS02275 Genome accession   NZ_CP113039
Coordinates   405064..405780 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain Gwen     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 400064..410780
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS086_RS02245 - 400281..400907 (+) 627 WP_267811088.1 nitroreductase family protein -
  OS086_RS02250 - 401268..402053 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  OS086_RS02255 hld 402653..402733 (-) 81 WP_000046022.1 delta-hemolysin -
  OS086_RS02260 - 403023..403586 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  OS086_RS02265 agrD 403589..403732 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  OS086_RS02270 agrC 403762..405045 (+) 1284 WP_001628454.1 quorum-sensing sensor histidine kinase AgrC -
  OS086_RS02275 agrA 405064..405780 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  OS086_RS02280 - 405852..405961 (+) 110 Protein_423 hypothetical protein -
  OS086_RS02285 - 406149..407108 (-) 960 WP_267811089.1 carbohydrate kinase family protein -
  OS086_RS02290 - 407105..408589 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  OS086_RS02295 - 408738..409688 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=759360 OS086_RS02275 WP_000688492.1 405064..405780(+) (agrA) [Staphylococcus aureus strain Gwen]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=759360 OS086_RS02275 WP_000688492.1 405064..405780(+) (agrA) [Staphylococcus aureus strain Gwen]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1