Detailed information NTG0759358

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OS086_RS01445
• Genome accession: NZ_CP113039
• Coordinates: 271014..272057 (-)
• Length: 347 a.a.
• NCBI ID: WP_267811077.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain Gwen
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 266014..277057

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OS086_RS01415	-	266435..267691 (-)	1257	WP_001795108.1	aminopeptidase	-
OS086_RS01420	-	267694..267894 (-)	201	WP_000180460.1	DUF1128 family protein	-
OS086_RS01425	-	268041..268505 (+)	465	WP_042109418.1	low molecular weight protein-tyrosine-phosphatase	-
OS086_RS01430	-	268512..268787 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
OS086_RS01435	-	269065..270282 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
OS086_RS01440	vraR	270395..271024 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
OS086_RS01445	vraS	271014..272057 (-)	1044	WP_267811077.1	sensor histidine kinase	Regulator
OS086_RS01450	liaF	272054..272755 (-)	702	Protein_257	cell wall-active antibiotics response protein LiaF	-
OS086_RS01455	-	272770..273156 (-)	387	WP_001110179.1	hypothetical protein	-
OS086_RS01460	map	273373..274131 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
OS086_RS01465	-	274662..275648 (+)	987	WP_000999717.1	FUSC family protein	-
OS086_RS01470	-	276079..276492 (-)	414	WP_001557448.1	hypothetical protein	-
OS086_RS01475	-	276521..276631 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40060.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=759358 OS086_RS01445 WP_267811077.1 271014..272057(-) (vraS) [Staphylococcus aureus strain Gwen]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDYKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=759358 OS086_RS01445 WP_267811077.1 271014..272057(-) (vraS) [Staphylococcus aureus strain Gwen]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTATAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997