Detailed information NTG0759317

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OS091_RS06240
• Genome accession: NZ_CP113037
• Coordinates: 1223408..1224451 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Zilean
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1218408..1229451

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OS091_RS06210	-	1218834..1218944 (+)	111	WP_001790257.1	hypothetical protein	-
OS091_RS06215	-	1218973..1219386 (+)	414	WP_025174552.1	hypothetical protein	-
OS091_RS06220	-	1219819..1220805 (-)	987	WP_000999708.1	FUSC family protein	-
OS091_RS06225	map	1221334..1222092 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
OS091_RS06230	-	1222309..1222695 (+)	387	WP_001110179.1	hypothetical protein	-
OS091_RS06235	liaF	1222710..1223411 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
OS091_RS06240	vraS	1223408..1224451 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OS091_RS06245	vraR	1224441..1225070 (+)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
OS091_RS06250	-	1225183..1226400 (-)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
OS091_RS06255	-	1226678..1226953 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
OS091_RS06260	-	1226960..1227424 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
OS091_RS06265	-	1227571..1227771 (+)	201	WP_000180460.1	DUF1128 family protein	-
OS091_RS06270	-	1227774..1229030 (+)	1257	WP_078065149.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=759317 OS091_RS06240 WP_001017131.1 1223408..1224451(+) (vraS) [Staphylococcus aureus strain Zilean]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=759317 OS091_RS06240 WP_001017131.1 1223408..1224451(+) (vraS) [Staphylococcus aureus strain Zilean]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1