Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   OS083_RS06905 Genome accession   NZ_CP113027
Coordinates   1333122..1333838 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain Syndra     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1328122..1338838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS083_RS06885 - 1329216..1330166 (+) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -
  OS083_RS06890 - 1330315..1331799 (+) 1485 WP_000141422.1 sucrose-6-phosphate hydrolase -
  OS083_RS06895 - 1331796..1332755 (+) 960 WP_001253300.1 carbohydrate kinase family protein -
  OS083_RS06900 - 1332943..1333050 (-) 108 WP_031844951.1 hypothetical protein -
  OS083_RS06905 agrA 1333122..1333838 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  OS083_RS06910 agrC 1333857..1335149 (-) 1293 WP_267813958.1 quorum-sensing sensor histidine kinase AgrC -
  OS083_RS06915 agrD 1335174..1335314 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  OS083_RS06920 agrB 1335311..1335880 (-) 570 WP_001105712.1 accessory gene regulator AgrB -
  OS083_RS15105 hld 1336170..1336250 (+) 81 WP_000046023.1 delta-hemolysin -
  OS083_RS06930 - 1336849..1337634 (-) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  OS083_RS06935 - 1337995..1338621 (-) 627 WP_000522383.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=759188 OS083_RS06905 WP_000688492.1 1333122..1333838(-) (agrA) [Staphylococcus aureus strain Syndra]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=759188 OS083_RS06905 WP_000688492.1 1333122..1333838(-) (agrA) [Staphylococcus aureus strain Syndra]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1