Detailed information NTG0759146

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OS090_RS07035
• Genome accession: NZ_CP113018
• Coordinates: 1334574..1335617 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Taliyah
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1329574..1340617

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OS090_RS07005	-	1329944..1330054 (+)	111	WP_001790257.1	hypothetical protein	-
OS090_RS07010	-	1330083..1330496 (+)	414	WP_001549145.1	hypothetical protein	-
OS090_RS07015	-	1330927..1331913 (-)	987	WP_000999713.1	FUSC family protein	-
OS090_RS07020	map	1332500..1333258 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
OS090_RS07025	-	1333475..1333861 (+)	387	WP_001110179.1	hypothetical protein	-
OS090_RS07030	liaF	1333876..1334577 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
OS090_RS07035	vraS	1334574..1335617 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OS090_RS07040	vraR	1335607..1336236 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
OS090_RS07045	-	1336352..1337569 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
OS090_RS07050	-	1337847..1338122 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
OS090_RS07055	-	1338129..1338593 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
OS090_RS07060	-	1338740..1338940 (+)	201	WP_000180461.1	DUF1128 family protein	-
OS090_RS07065	-	1338943..1340199 (+)	1257	WP_001795438.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=759146 OS090_RS07035 WP_001017131.1 1334574..1335617(+) (vraS) [Staphylococcus aureus strain Taliyah]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=759146 OS090_RS07035 WP_001017131.1 1334574..1335617(+) (vraS) [Staphylococcus aureus strain Taliyah]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1