Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   OS077_RS00610 Genome accession   NZ_CP113016
Coordinates   116077..116793 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain Azir     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 111077..121793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS077_RS00580 - 111297..111923 (+) 627 WP_000522384.1 nitroreductase family protein -
  OS077_RS00585 - 112284..113069 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  OS077_RS14440 hld 113666..113746 (-) 81 WP_000046022.1 delta-hemolysin -
  OS077_RS00595 - 114036..114599 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  OS077_RS00600 agrD 114602..114745 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  OS077_RS00605 agrC 114775..116058 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  OS077_RS00610 agrA 116077..116793 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  OS077_RS00615 - 116873..116982 (+) 110 Protein_118 hypothetical protein -
  OS077_RS00620 - 117170..118129 (-) 960 WP_001253314.1 carbohydrate kinase family protein -
  OS077_RS00625 - 118126..119610 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  OS077_RS00630 - 119759..120709 (-) 951 WP_031588340.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=759091 OS077_RS00610 WP_000688498.1 116077..116793(+) (agrA) [Staphylococcus aureus strain Azir]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=759091 OS077_RS00610 WP_000688498.1 116077..116793(+) (agrA) [Staphylococcus aureus strain Azir]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996