Detailed information NTG0759090

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OS077_RS00155
• Genome accession: NZ_CP113016
• Coordinates: 28615..29658 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Azir
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 23615..34658

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OS077_RS00125	-	24037..25293 (-)	1257	WP_267836789.1	aminopeptidase	-
OS077_RS00130	-	25296..25496 (-)	201	WP_000180460.1	DUF1128 family protein	-
OS077_RS00135	-	25643..26107 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
OS077_RS00140	-	26114..26389 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
OS077_RS00145	-	26667..27884 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
OS077_RS00150	vraR	27996..28625 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
OS077_RS00155	vraS	28615..29658 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OS077_RS00160	liaF	29655..30356 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
OS077_RS00165	-	30371..30757 (-)	387	WP_001110179.1	hypothetical protein	-
OS077_RS00170	map	30974..31732 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
OS077_RS00175	-	32144..33130 (+)	987	WP_000999713.1	FUSC family protein	-
OS077_RS00180	-	33561..33974 (-)	414	WP_001670387.1	hypothetical protein	-
OS077_RS00185	-	34003..34113 (-)	111	WP_031775032.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=759090 OS077_RS00155 WP_001017131.1 28615..29658(-) (vraS) [Staphylococcus aureus strain Azir]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=759090 OS077_RS00155 WP_001017131.1 28615..29658(-) (vraS) [Staphylococcus aureus strain Azir]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1