Detailed information NTG0759083

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OS078_RS13750
• Genome accession: NZ_CP113015
• Coordinates: 2710228..2711271 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Zed
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2705228..2716271

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OS078_RS13720	-	2705646..2706902 (-)	1257	WP_001795438.1	aminopeptidase	-
OS078_RS13725	-	2706905..2707105 (-)	201	WP_000180461.1	DUF1128 family protein	-
OS078_RS13730	-	2707252..2707716 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
OS078_RS13735	-	2707723..2707998 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
OS078_RS13740	-	2708276..2709493 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
OS078_RS13745	vraR	2709609..2710238 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
OS078_RS13750	vraS	2710228..2711271 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OS078_RS13755	liaF	2711268..2711969 (-)	702	WP_267836463.1	cell wall-active antibiotics response protein LiaF	-
OS078_RS13760	-	2711984..2712370 (-)	387	WP_001110179.1	hypothetical protein	-
OS078_RS13765	map	2712587..2713345 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
OS078_RS13770	-	2713932..2714918 (+)	987	WP_000999713.1	FUSC family protein	-
OS078_RS13775	-	2715349..2715762 (-)	414	WP_001549145.1	hypothetical protein	-
OS078_RS13780	-	2715791..2715901 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=759083 OS078_RS13750 WP_001017131.1 2710228..2711271(-) (vraS) [Staphylococcus aureus strain Zed]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=759083 OS078_RS13750 WP_001017131.1 2710228..2711271(-) (vraS) [Staphylococcus aureus strain Zed]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1