Detailed information NTG0758967

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OS082_RS06735
• Genome accession: NZ_CP113007
• Coordinates: 1313540..1314583 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Ryze
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1308540..1319583

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OS082_RS06705	-	1308910..1309020 (+)	111	WP_001790257.1	hypothetical protein	-
OS082_RS06710	-	1309049..1309462 (+)	414	WP_001549145.1	hypothetical protein	-
OS082_RS06715	-	1309893..1310879 (-)	987	WP_000999713.1	FUSC family protein	-
OS082_RS06720	map	1311466..1312224 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
OS082_RS06725	-	1312441..1312827 (+)	387	WP_001110179.1	hypothetical protein	-
OS082_RS06730	liaF	1312842..1313543 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
OS082_RS06735	vraS	1313540..1314583 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OS082_RS06740	vraR	1314573..1315202 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
OS082_RS06745	-	1315318..1316535 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
OS082_RS06750	-	1316813..1317088 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
OS082_RS06755	-	1317095..1317559 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
OS082_RS06760	-	1317706..1317906 (+)	201	WP_000180461.1	DUF1128 family protein	-
OS082_RS06765	-	1317909..1319165 (+)	1257	WP_001795438.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=758967 OS082_RS06735 WP_001017131.1 1313540..1314583(+) (vraS) [Staphylococcus aureus strain Ryze]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=758967 OS082_RS06735 WP_001017131.1 1313540..1314583(+) (vraS) [Staphylococcus aureus strain Ryze]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1