Detailed information NTG0758941

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OS073_RS07755
• Genome accession: NZ_CP113005
• Coordinates: 1496762..1497805 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Galio
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1491762..1502805

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OS073_RS07725	-	1492180..1493436 (-)	1257	WP_001795438.1	aminopeptidase	-
OS073_RS07730	-	1493439..1493639 (-)	201	WP_000180461.1	DUF1128 family protein	-
OS073_RS07735	-	1493786..1494250 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
OS073_RS07740	-	1494257..1494532 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
OS073_RS07745	-	1494810..1496027 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
OS073_RS07750	vraR	1496143..1496772 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
OS073_RS07755	vraS	1496762..1497805 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OS073_RS07760	liaF	1497802..1498503 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
OS073_RS07765	-	1498518..1498904 (-)	387	WP_001110179.1	hypothetical protein	-
OS073_RS07770	map	1499121..1499879 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
OS073_RS07775	-	1500466..1501452 (+)	987	WP_000999713.1	FUSC family protein	-
OS073_RS07780	-	1501883..1502296 (-)	414	WP_001549145.1	hypothetical protein	-
OS073_RS07785	-	1502325..1502435 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=758941 OS073_RS07755 WP_001017131.1 1496762..1497805(-) (vraS) [Staphylococcus aureus strain Galio]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=758941 OS073_RS07755 WP_001017131.1 1496762..1497805(-) (vraS) [Staphylococcus aureus strain Galio]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1