Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraS   Type   Regulator
Locus tag   ORT68_RS04570 Genome accession   NZ_CP111111
Coordinates   970307..971353 (+) Length   348 a.a.
NCBI ID   WP_001830374.1    Uniprot ID   A0A0N1EGU4
Organism   Staphylococcus epidermidis strain KCTC 13172     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 965307..976353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ORT68_RS04545 (ORT68_04545) isaB 966448..966984 (+) 537 WP_002470337.1 immunodominant staphylococcal antigen IsaB family protein -
  ORT68_RS04550 (ORT68_04550) - 967135..968121 (-) 987 WP_001830388.1 FUSC family protein -
  ORT68_RS04555 (ORT68_04555) map 968295..969050 (+) 756 WP_001830397.1 type I methionyl aminopeptidase -
  ORT68_RS04560 (ORT68_04560) - 969208..969594 (+) 387 WP_001830382.1 hypothetical protein -
  ORT68_RS04565 (ORT68_04565) liaF 969609..970310 (+) 702 WP_001830436.1 cell wall-active antibiotics response protein LiaF -
  ORT68_RS04570 (ORT68_04570) vraS 970307..971353 (+) 1047 WP_001830374.1 sensor histidine kinase Regulator
  ORT68_RS04575 (ORT68_04575) vraR 971343..971972 (+) 630 WP_001830439.1 two-component system response regulator VraR Regulator
  ORT68_RS04580 (ORT68_04580) - 972029..973207 (-) 1179 WP_001830411.1 YihY/virulence factor BrkB family protein -
  ORT68_RS04585 (ORT68_04585) - 973614..973898 (-) 285 WP_001830401.1 YtxH domain-containing protein -
  ORT68_RS04590 (ORT68_04590) - 973906..974370 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  ORT68_RS04595 (ORT68_04595) - 974511..974726 (+) 216 WP_001830421.1 DUF1128 domain-containing protein -
  ORT68_RS04600 (ORT68_04600) - 974728..975969 (+) 1242 WP_001832467.1 aminopeptidase -

Sequence

Protein


Download         Length: 348 a.a.        Molecular weight: 40066.49 Da        Isoelectric Point: 5.8512

>NTDB_id=757914 ORT68_RS04570 WP_001830374.1 970307..971353(+) (vraS) [Staphylococcus epidermidis strain KCTC 13172]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide


Download         Length: 1047 bp        

>NTDB_id=757914 ORT68_RS04570 WP_001830374.1 970307..971353(+) (vraS) [Staphylococcus epidermidis strain KCTC 13172]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(249-340)

Histidine kinase (HisKA_3)

(147-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0N1EGU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraS Staphylococcus aureus N315

93.023

98.851

0.92